Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

X-ray Diffraction of Biological Samples01:10

X-ray Diffraction of Biological Samples

5.2K
X-ray diffraction or XRD is an analytical tool that utilizes X-rays to study ordered structures such as crystalline organic and inorganic samples, polycrystalline materials, proteins, carbohydrates, and drugs.
According to Bragg's law, when X-rays strike the sample positioned on a stage, the rays are  scattered by the electron clouds around the sample atoms. The  X-ray diffraction or scattering is caused by constructive interference of the X-ray waves that reflect off the internal...
5.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Target-switchable molecular imaging platform for 3D protein mapping in single cells by synchrotron radiation hard X-ray nanotomography.

Talanta·2026
Same author

Nano-Confined Radical Anion as An NIR-II Photothermal Immunogenic Amplifier for In Situ Cancer Vaccination.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026
Same author

Adaptive Protein Corona Nanoassemblies Couple Cytokine Signaling with Endogenous Antigen Transport for Systemic Cancer Immunity.

Journal of the American Chemical Society·2026
Same author

Navigating the transcytosis highway: engineering protein coronas for enhanced drug delivery across the blood-brain barrier.

Science bulletin·2026
Same author

Chiral nanoparticles drive enantiomer-specific osteogenic differentiation of stem cells and accelerate bone regeneration.

Science advances·2026
Same author

Restoration of endogenous electric fields with a glucose-powered symbiotic bioabsorbable bandage for diabetic wound healing.

Science advances·2026

Related Experiment Video

Updated: Apr 13, 2026

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.6K

Synchrotron radiation techniques for nanotoxicology.

Yu-Feng Li1, Jiating Zhao1, Ying Qu2

  • 1CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, and Laboratory of Metallomics and Nanometallomics, Institute of High Energy Physics, Chinese Academy of Sciences, Beijing, China.

Nanomedicine : Nanotechnology, Biology, and Medicine
|May 3, 2015
PubMed
Summary
This summary is machine-generated.

Synchrotron radiation techniques are essential for understanding engineered nanomaterial interactions with biological systems. This review highlights their role in assessing nanomaterial behavior and safety across various environments.

Keywords:
EcotoxicologyIn vitroIn vivoNanotoxicologySynchrotron radiation

More Related Videos

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis
08:26

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis

Published on: December 10, 2019

10.3K
Preparation of Nanoparticles for ToF-SIMS and XPS Analysis
06:24

Preparation of Nanoparticles for ToF-SIMS and XPS Analysis

Published on: September 13, 2020

9.4K

Related Experiment Videos

Last Updated: Apr 13, 2026

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages
08:46

Using Synchrotron Radiation Microtomography to Investigate Multi-scale Three-dimensional Microelectronic Packages

Published on: April 13, 2016

10.6K
Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis
08:26

Cell Culture on Silicon Nitride Membranes and Cryopreparation for Synchrotron X-ray Fluorescence Nano-analysis

Published on: December 10, 2019

10.3K
Preparation of Nanoparticles for ToF-SIMS and XPS Analysis
06:24

Preparation of Nanoparticles for ToF-SIMS and XPS Analysis

Published on: September 13, 2020

9.4K

Area of Science:

  • Nanotoxicology and materials science.
  • Investigating the biological interactions of engineered nanomaterials.

Background:

  • Increasing use of nanomaterials necessitates robust nanotoxicity assessment.
  • Traditional toxicology methods may not fully capture nanoparticle-specific mechanisms.
  • Challenges exist in real-time, in situ measurements within biological microenvironments.

Purpose of the Study:

  • To review the indispensable role of synchrotron radiation techniques in nanotoxicology.
  • To summarize applications in screening nanomaterial characteristics and behaviors.
  • To discuss ecotoxicological effects of engineered nanomaterials.

Main Methods:

  • Utilizing synchrotron radiation's properties: high polarization and tunability.
  • Application of synchrotron-based techniques for physicochemical characterization.
  • In vitro and in vivo studies of nanomaterial interactions.
  • Ecotoxicological assessments using synchrotron radiation.

Main Results:

  • Synchrotron radiation enables detailed screening of nanomaterial properties.
  • Techniques facilitate understanding of in vitro and in vivo nanomaterial behavior.
  • Synchrotron methods contribute to assessing ecotoxicological impacts.

Conclusions:

  • Synchrotron radiation is a powerful, versatile tool for comprehensive nanotoxicology studies.
  • It aids in understanding nanomaterial safety and environmental impact.
  • Underlying principles are applicable to various scientific fields beyond nanotoxicology.