Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

PathFound: An agentic multimodal model activating evidence-seeking pathological diagnosis.

Medical image analysis·2026
Same author

A novel pH-responsive nanoreactor for pyroptosis induction: multifaceted ROS amplification drives potent immunotherapy against triple-negative breast cancer.

Journal of nanobiotechnology·2026
Same author

[Dietary sodium intake and food sources among adult residents in 16 provinces (autonomous regions and municipalities) of China from 2022-2024].

Wei sheng yan jiu = Journal of hygiene research·2026
Same author

Multilayer brain network analysis in mice reveals ketamine-induced reorganization of brain- wide fluctuations and gut-brain axis.

Communications biology·2026
Same author

Towards the construction of a virtual yeast.

Nature·2026
Same author

Investigations on the Multicentered Active Sites of Ziegler-Natta Polypropylene Catalysts through Multi-Models of the MgCl<sub>2</sub> Support.

ACS omega·2026

Related Experiment Video

Updated: Apr 13, 2026

Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent
08:31

Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent

Published on: November 30, 2017

13.0K

Canonical correlation between LFP network and spike network during working memory task in rat.

Hu Yi1, Xiaofan Zhang1, Wenwen Bai1

  • 1School of Biomedical Engineering, Tianjin Medical University, Tianjin, 300070, China.

Behavioural Brain Research
|May 3, 2015
PubMed
Summary

This study reveals enhanced coordination between brain networks during working memory tasks. Analyzing local field potentials (LFPs) and neural spikes, researchers found increased network integration is crucial for cognitive function.

Keywords:
Canonical correlation analysisLFP networkRatSpike networkWorking memory

More Related Videos

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
10:46

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

Published on: June 22, 2017

16.6K
Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice
08:59

Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice

Published on: May 26, 2023

4.1K

Related Experiment Videos

Last Updated: Apr 13, 2026

Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent
08:31

Concurrent Recording of Co-localized Electroencephalography and Local Field Potential in Rodent

Published on: November 30, 2017

13.0K
Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats
10:46

Acute In Vivo Electrophysiological Recordings of Local Field Potentials and Multi-unit Activity from the Hyperdirect Pathway in Anesthetized Rats

Published on: June 22, 2017

16.6K
Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice
08:59

Author Spotlight: Advancements in Multichannel Extracellular Recording for Studying Neuronal Activity in Freely Moving Mice

Published on: May 26, 2023

4.1K

Area of Science:

  • Neuroscience
  • Cognitive Neuroscience
  • Systems Neuroscience

Background:

  • Working memory involves temporary information storage and manipulation.
  • Local field potentials (LFPs) and neuronal spikes, along with their coordination, are implicated in working memory mechanisms.
  • Existing methods for LFP-spike coordination often analyze signals in isolation, neglecting the brain's network properties.

Purpose of the Study:

  • To investigate the coordination between the local field potential (LFP) network and the spike network for a deeper understanding of working memory.
  • To explore how network-level interactions contribute to working memory processes.

Main Methods:

  • Simultaneous recording of multi-channel LFPs and spikes in the rat prefrontal cortex during a Y-maze working memory task.
  • Estimation of functional connectivity within the LFP network using Directed Transfer Function (DTF).
  • Estimation of functional connectivity within the spike network using Maximum Likelihood Estimation (MLE).
  • Quantification of coordination between LFP and spike networks using Canonical Correlation Analysis (CCA).

Main Results:

  • Canonical Correlation (CC) values fluctuated throughout the working memory task.
  • The CC-curve exhibited a peak before the choice point, indicating a significant enhancement in coordination between the LFP and spike networks.
  • Working memory performance correlated with significantly higher CC values compared to the inter-trial interval.

Conclusions:

  • Enhanced canonical correlation between the LFP and spike networks suggests a potential mechanism for network integration in working memory.
  • This study highlights the importance of analyzing coordinated network activity for understanding cognitive functions like working memory.