[Changes in blood circulation in the post-resuscitation period of acute myocardial infarction]

Cardiac output and parameters of myocardial contractility in the post-resuscitation++ period of acute coronarogenic infarction were studied in experiments on dogs anesthetized with nembutal (40 mg/kg) (29 dogs). Twelve dogs reanimated after fibrillation-induced cardiac arrest were used as controls. The duration of clinical death was 5 minutes. The experimental animals showed a phase pattern of changes with initial hyperperfusion that was less pronounced in infarction and with subsequent one that was more profound than did the controls. A greater degree of +blood circulation disturbances were shown to be associated with high postresuscitation death rates. Diminished cardiac output is originally related to inhibited myocardial contractility; subsequently, of great importance are hypovolemia and arrhythmias.