Intensified association between waist circumference and hypertension in abdominally overweight children

Bin Dong1, Zhiqiang Wang1, Yide Yang2

  • 1Institute of Child and Adolescent Health, School of Public Health, Peking University Health Sciences Center, Beijing, China; Centre for Chronic Disease, School of Medicine, The University of Queensland, Herston, Queensland, Australia.

Insights

Abdominal adiposity significantly increases hypertension risk in children. Overweight children showed a 2.39 times higher risk, with waist circumference gains posing a greater threat in this group.

Area of Science:

  • Pediatrics
  • Cardiovascular Health
  • Public Health

Background:

  • Childhood hypertension is a growing concern, with abdominal adiposity identified as a key risk factor.
  • Understanding the relationship between waist circumference (WC) and hypertension is crucial for early intervention.

Purpose of the Study:

  • To compare the association strength between waist circumference (WC) and hypertension in children across different WC levels.
  • To quantify the increased risk of hypertension associated with abdominal adiposity in children.

Main Methods:

  • A large cohort of 82,413 Chinese children aged 9-17 years was analyzed.
  • Abdominal overweight was defined as WC ≥75th percentile; hypertension as ≥95th percentile.
  • Logistic regression models calculated odds ratios (OR) for hypertension based on WC z-scores.

Main Results:

  • Abdominally overweight children had a significantly higher risk of hypertension (OR: 2.39).
  • Each standard deviation increase in WC raised hypertension odds by 42% in normal WC children, and 74% in abdominally overweight children.
  • This intensified association was consistent across sexes, areas, and age groups (9-14 years).

Conclusions:

  • Abdominally overweight children exhibit a markedly intensified association between waist circumference and hypertension risk.
  • Intervention strategies targeting waist circumference reduction are vital for preventing childhood hypertension, especially in at-risk populations.
Abstract

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