Related Experiment Video
Updated: Apr 13, 2026

Setting-up an In Vitro Model of Rat Blood-brain Barrier BBB: A Focus on BBB Impermeability and Receptor-mediated Transport
Published on: June 28, 2014
Peptides at the blood brain barrier: Knowing me knowing you
Thomas P Davis1, Thomas J Abbruscato2, Richard D Egleton3
1The Davis Lab, Department of Medical Pharmacology, University of Arizona, Tucson, AZ 85724-5050.
Abstract:
When the Davis Lab was first asked to contribute to this special edition of Peptides to celebrate the career and influence of Abba Kastin on peptide research, it felt like a daunting task. It is difficult to really understand and appreciate the influence that Abba has had, not only on a generation of peptide researchers, but also on the field of blood brain barrier (BBB) research, unless you lived it as we did. When we look back at our careers and those of our former students, one can truly see that several of Abba's papers played an influential role in the development of our personal research programs.
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