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Updated: Apr 13, 2026

Polygraphic Recording Procedure for Measuring Sleep in Mice
Published on: January 25, 2016
Synthetic melatoninergic ligands: achievements and prospects
N V Kostiuk1, M B Belyakova2, D V Leshchenko2
1Department of Biology, Tver State Medical Academy, 4 Sovetskaya Street, Tver 170100, Russia.
Abstract:
Pineal hormone melatonin is widely used in the treatment of disorders of circadian rhythms. The presence of melatonin receptors in various animal tissues motivates the use of this hormone in some other diseases. For this reason, in recent years investigators continued the search for synthetic analogues of melatonin which are metabolically stable and selective to receptors. This review includes recent information about the most famous melatonin analogues, their structure, properties, and physiological features of the interaction with melatonin receptors.
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