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Deformable Surface Accommodating Intraocular Lens: Second Generation Prototype Design Methodology and Testing.

Sean J McCafferty¹, Jim T Schwiegerling²

¹Intuor Technologies - CEO; Arizona Eye Consultants - Partner; University of Arizona Department of Ophthalmology Clinical Assistant Professor; University of Arizona College of Optical Science.

Translational Vision Science & Technology

|May 5, 2015

Summary

This summary is machine-generated.

This study presents a new accommodating intraocular lens with a deformable interface. The design optimizes optical and mechanical performance for improved vision within the eye's natural focusing capabilities.

Keywords:

accommodation cataract surgery lens optics physiological optics

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Area of Science:

Ophthalmology
Biomechanical Engineering
Optical Science

Background:

Presbyopia correction remains a challenge in ophthalmology.
Accommodating intraocular lenses (IOLs) aim to restore the eye's natural focusing ability.
Deformable interface IOLs offer a promising approach to achieving accommodation.

Purpose of the Study:

To present an analysis methodology for developing and evaluating accommodating intraocular lenses (IOLs) with a deformable interface.
To optimize the design of a next-generation extruded gel interface IOL.

Main Methods:

A prototype deformable interface IOL was designed and tested.
Measurements included actuation force, lens power, and optical performance (OTF, Strehl ratio).
Mathematical models, verified by the prototype, were used to optimize design parameters.

Main Results:

The prototype IOL achieved adequate image quality using physiologic accommodating forces.
Mathematical modeling identified optimal parameters: max gel thickness/diameter ratio, max refractive index change, and min gel material properties (Poisson's ratio, Young's modulus).
Maximized optical and mechanical performance was achieved by minimizing asphericity and actuation pressure.

Conclusions:

The deformable interface IOL prototype performed well within the eye's physiologic constraints.
The design allows for full accommodative amplitude and maintains image quality.
The delineated design parameters can serve as a template for future deformable interface IOL development.