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Updated: Apr 13, 2026

Setting-up an In Vitro Model of Rat Blood-brain Barrier BBB: A Focus on BBB Impermeability and Receptor-mediated Transport
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Quantitative Analysis of the Enhanced Permeation and Retention (EPR) Effect

Andrew D Wong1, Mao Ye2, Martin B Ulmschneider1

  • 1Department of Materials Science and Engineering, Johns Hopkins University, Baltimore, Maryland, United States of America; Institute for Nanobiotechnology (INBT), Johns Hopkins University, Baltimore, Maryland, United States of America.

Plos One
|May 5, 2015
PubMed

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