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Chronic iritis associated with cutaneous leukocytoclastic vasculitis
Jessica Lambert1, Alexis Rodriguez1, Mischelle Pearcy-Baluyot1
1U.S. Department of Veterans Affairs, Malcom Randall VAMC, VA Optometry Clinic, 5533 SW 64th Street, Gainesville, FL.
Military Medicine
|May 5, 2015
Summary
Cutaneous leukocytoclastic vasculitis (LCV) can cause chronic iritis, often remaining undiagnosed for years. Early diagnosis through skin biopsy and serological testing is crucial for managing this systemic condition.
Area of Science:
- Dermatology
- Ophthalmology
- Rheumatology
Background:
- Cutaneous leukocytoclastic vasculitis (LCV) is a systemic small-vessel vasculitis.
- It manifests as palpable, purpuric skin lesions resulting from cutaneous blood vessel destruction.
Observation:
- LCV can be associated with iritis, an inflammation of the eye's iris.
- Patients may present with chronic iritis of unknown etiology, masking underlying LCV.
- The study highlights a case where chronic iritis was eventually linked to LCV.
Findings:
- LCV and iritis share a significant correlation, though diagnosis can be delayed.
- Systemic Sjogren's syndrome is also frequently linked with LCV.
- Diagnostic tools include serological testing, imaging, and skin biopsy.
Implications:
- Emphasizes the importance of considering LCV in patients with unexplained chronic iritis.
- Highlights the need for comprehensive diagnostic workups, including skin biopsy and serology.
- Underscores the potential for delayed diagnosis and the systemic nature of LCV.
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