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Reliability and validity of the Advanced Basal Cell Carcinoma Index (aBCCdex)
S D Mathias1, M M Chren2, R D Crosby3
1Health Outcomes Solutions, 2351 Via Tuscany, Winter Park, FL, 32789, U.S.A.
The British Journal of Dermatology
|May 6, 2015
Summary
A new questionnaire, the aBCCdex, was developed and validated for patients with advanced basal cell carcinoma (aBCC) and basal cell carcinoma naevus syndrome (BCCNS). It demonstrated good reliability and validity for assessing patient-reported outcomes.
Area of Science:
- Dermatology
- Health Outcomes Research
- Psychometrics
Background:
- Newly developed patient-reported outcome (PRO) questionnaires exist for advanced basal cell carcinoma (aBCC) and basal cell carcinoma naevus syndrome (BCCNS).
- Validation of these PRO tools is crucial for accurate patient assessment.
Purpose of the Study:
- To evaluate the measurement properties of newly developed PRO questionnaires for patients with aBCC or BCCNS.
- To establish the reliability and validity of these instruments for clinical use.
Main Methods:
- 129 patients with aBCC or BCCNS completed two new questionnaires multiple times over 3 months.
- Psychometric evaluation included internal consistency, test-retest reliability, construct validity, known-groups validity, and responsiveness.
- Collateral measures (Skindex-16, SF-12) were used to assess validity.
Main Results:
- The two questionnaires were combined into a single instrument, the aBCCdex.
- The aBCCdex demonstrated acceptable internal consistency and significant correlations with conceptually similar scales.
- The aBCCdex showed known-groups validity and responsiveness to change.
Conclusions:
- The aBCCdex is a brief, comprehensive, reliable, and valid questionnaire for patients with aBCC and BCCNS.
- Further research is needed to determine the minimally important difference in a larger population.
