Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Chromatography: Types of Detectors-II01:19

Gas Chromatography: Types of Detectors-II

1.5K
In gas chromatography, different detectors are employed to meet specific analytical needs. These detectors are often categorized based on their detection mechanisms and the types of compounds they are best suited to analyze. Thermal Conductivity Detectors (TCD), Flame Ionization Detectors (FID), and Electron Capture Detectors (ECD) represent common categories, each with unique operating principles and applications. However, beyond these, several other detectors are designed for more specialized...
1.5K
Gas Chromatography: Overview of Detectors01:13

Gas Chromatography: Overview of Detectors

2.6K
Detectors in gas chromatography (GC) help identify and quantify the components of a mixture by translating chemical properties into measurable signals, which are displayed on a chromatogram. Detectors can be categorized into two main types: destructive and non-destructive.
A non-destructive detector allows a sample to be analyzed without altering or consuming it, meaning the sample can be collected after detection for further analysis. Examples include thermal conductivity detectors and...
2.6K
Gas Chromatography–Mass Spectrometry (GC–MS)01:14

Gas Chromatography–Mass Spectrometry (GC–MS)

7.9K
Gas chromatography–mass spectrometry (GC–MS) is the combination of analytical techniques of gas chromatography and mass spectrometry in a single instrument for analyzing a mixture of compounds. The gas chromatograph separates the compounds in the mixture, and the mass spectrometer analyzes each compound separately to determine the molecular masses and molecular structures.
A gas chromatograph consists of a long, narrow capillary column with a polysiloxane coating on the inner wall....
7.9K
Gas Chromatography: Types of Detectors-I01:21

Gas Chromatography: Types of Detectors-I

2.1K
There are different types of detectors used in gas chromatography, each with its own specific properties that make it suitable for detecting certain types of analytes. The most commonly used detectors in GC are thermal conductivity detector (TCD), flame ionization detector (FID), and electron capture detector (ECD).
TCD is the earliest and most widely used detector that operates by measuring the changes in the thermal conductivity of the carrier gas. When a sample compound enters the detector,...
2.1K
Gas Chromatography: Introduction01:13

Gas Chromatography: Introduction

4.9K
Gas chromatography (GC) is a technique for separating and analyzing volatile compounds in a sample. Its primary purpose is to identify and quantify components in complex mixtures, making it essential in fields such as environmental analysis, pharmaceuticals, and petrochemicals. GC is also called vapor-phase chromatography (VPC) or gas-liquid partition chromatography (GLPC).
In GC,  a sample is vaporized and mixed with an inert carrier gas (the mobile phase), which transports it through a...
4.9K
Gas Chromatography: Sample Injection Systems01:08

Gas Chromatography: Sample Injection Systems

2.0K
In gas chromatography, the sample is introduced as a vapor plug into the carrier gas stream for high efficiency and resolution. A microsyringe injects the sample solution into a heated sample port, vaporizing it and mixing it with the carrier gas. This process is important to ensure the sample is properly prepared for analysis. Thermally sensitive samples can be injected directly into the column and volatilized by slowly increasing the column temperature.
Two primary injection methods are used...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Characterization of the oxygen properties of a hybrid glass chip designed for precise on chip oxygen control.

Lab on a chip·2025
Same author

Addressing underestimation of waterborne disease risks due to fecal indicator bacteria bound in aggregates.

Journal of applied microbiology·2024
Same author

Monitoring a planetary resource under threat.

Nature reviews. Chemistry·2024
Same author

Precise and fast control of the dissolved oxygen level for tumor-on-chip.

Lab on a chip·2022
Same author

Teriparatide Treatment Improves Bone Defect Healing Via Anabolic Effects on New Bone Formation and Non-Anabolic Effects on Inhibition of Mast Cells in a Murine Cranial Window Model.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research·2017
Same author

Yield-stress fluids foams: flow patterns and controlled production in T-junction and flow-focusing devices.

Soft matter·2016

Related Experiment Video

Updated: Apr 13, 2026

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
07:57

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

Published on: July 25, 2014

20.5K

Enhanced microgas chromatography using correlation techniques for continuous indoor pollutant detection.

William Cesar1,2, Frédéric Flourens1, Claire Kaiser3

  • 1†Université Paris-Est, ESIEE-Paris, ESYCOM, 2 Boulevard Blaise Pascal 93162 Noisy-le-Grand Cedex, France.

Analytical Chemistry
|May 6, 2015
PubMed
Summary

Stochastic injection techniques in microgas chromatographs (μGC) enable continuous, rapid detection of toxic gases. This approach significantly improves detection limits for enhanced air quality monitoring.

More Related Videos

Analyzing the Photo-oxidation of 2-propanol at Indoor Air Level Concentrations Using Field Asymmetric Ion Mobility Spectrometry
08:23

Analyzing the Photo-oxidation of 2-propanol at Indoor Air Level Concentrations Using Field Asymmetric Ion Mobility Spectrometry

Published on: June 14, 2018

9.3K
Measuring Dissolved Methane in Aquatic Ecosystems Using An Optical Spectroscopy Gas Analyzer
05:00

Measuring Dissolved Methane in Aquatic Ecosystems Using An Optical Spectroscopy Gas Analyzer

Published on: July 26, 2024

1.2K

Related Experiment Videos

Last Updated: Apr 13, 2026

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector
07:57

Quantitative Detection of Trace Explosive Vapors by Programmed Temperature Desorption Gas Chromatography-Electron Capture Detector

Published on: July 25, 2014

20.5K
Analyzing the Photo-oxidation of 2-propanol at Indoor Air Level Concentrations Using Field Asymmetric Ion Mobility Spectrometry
08:23

Analyzing the Photo-oxidation of 2-propanol at Indoor Air Level Concentrations Using Field Asymmetric Ion Mobility Spectrometry

Published on: June 14, 2018

9.3K
Measuring Dissolved Methane in Aquatic Ecosystems Using An Optical Spectroscopy Gas Analyzer
05:00

Measuring Dissolved Methane in Aquatic Ecosystems Using An Optical Spectroscopy Gas Analyzer

Published on: July 26, 2024

1.2K

Area of Science:

  • Analytical Chemistry
  • Environmental Science
  • Microtechnology

Background:

  • Standard laboratory chromatographs are bulky and slow for real-time monitoring.
  • Microgas chromatographs (μGC) offer miniaturization and faster analysis but face limitations in detection sensitivity.
  • Continuous monitoring of airborne contaminants is crucial for public health and safety.

Purpose of the Study:

  • To implement and validate stochastic injection techniques in a silicon-based microgas chromatograph (μGC).
  • To assess the performance improvements in terms of temporal resolution and limit of detection compared to traditional methods.
  • To explore the potential of μGC with stochastic injection for ubiquitous air quality monitoring.

Main Methods:

  • Development of a proof-of-concept silicon-based microgas chromatograph (μGC).
  • Integration and application of stochastic injection techniques within the μGC system.
  • Comparative analysis of detection limits and temporal resolution against standard single-injection techniques.

Main Results:

  • Demonstrated successful implementation of stochastic injection in a μGC.
  • Achieved high temporal resolution (5 s) for continuous gas detection.
  • Observed order-of-magnitude improvements in the limit of detection compared to single-injection methods.

Conclusions:

  • Stochastic injection techniques significantly enhance the performance of μGC systems.
  • This advancement enables continuous, sensitive detection of pollutants and toxic gases.
  • The technology holds promise for widespread use in indoor air quality monitoring devices.