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HTT-DB: horizontally transferred transposable elements database.
Bruno Reis Dotto1, Evelise Leis Carvalho2, Alexandre Freitas Silva1
1Campus São Gabriel, Universidade Federal do Pampa, São Gabriel.
Bioinformatics (Oxford, England)
|May 6, 2015
Summary
Horizontal transfer of transposable elements (HTTE) is a significant evolutionary force. The new HTT-DB database provides an accessible platform to explore over 300 documented cases of HTTE, aiding genomic evolutionary impact studies.
Area of Science:
- Genomics
- Evolutionary Biology
Background:
- Horizontal transfer of transposable elements (HTT) among eukaryotes, first identified in the 1980s, has over 300 documented cases.
- Recent discoveries highlight the profound evolutionary impact of HTT on host genomes.
Purpose of the Study:
- To develop an up-to-date, interactive, and expandable database for cataloging Horizontal Transfer of Transposable elements (HTT) events.
- To facilitate research on the evolutionary significance of HTT in eukaryotic genomes.
Main Methods:
- Development of the HTT-DB database using Java and MySQL.
- Ensuring compatibility with all major web browsers.
- Utilizing free tools and software packages for personal or non-profit use.
Main Results:
- The HTT-DB database offers easy access to a comprehensive collection of reported HTT cases.
- Users can retrieve detailed information for each HTT event.
- The database enables the generation and export of tables and graphs based on Transposable elements and host species classifications.
Conclusions:
- HTT-DB serves as a valuable, freely accessible resource for researchers studying the evolutionary impact of transposable elements.
- The database supports data-driven analysis and visualization of HTT events across eukaryotic species.
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