[Osteomyelitis: a probable, uncommon etiology agent]

F Cuoco1, I Borzani, M Torcoletti

  • 1UOS Reumatologia Pediatrica, Clinica Pediatrica De Marchi, IRCCS Cà Granda Ospedale Maggiore Policlino, Milano, Italia - cuoco.federica@gmail.com.

Minerva Pediatrica
|May 6, 2015
PubMed

Insights

Kingella kingae is an emerging cause of septic arthritis in young children, often presenting subtly. Early MRI can help differentiate K. kingae from other bacterial infections in pediatric osteoarticular cases.

Area of Science:

  • Pediatric Rheumatology
  • Pediatric Infectious Diseases
  • Pediatric Orthopedic Infections

Background:

  • Septic arthritis accounts for 6.5% of childhood arthritides, often arising from hematogenous spread or direct extension of infection.
  • Commonly implicated bacteria include Staphylococcus aureus and streptococci, but Kingella kingae is increasingly recognized in children under four.
  • Systemic signs like fever and bone pain, alongside local tenderness, often indicate septic arthritis.

Observation:

  • Kingella kingae infections in children typically present with subtle clinical signs and mild inflammatory responses.
  • Affected children may exhibit few overt signs of osteoarticular infection, complicating diagnosis.
  • Early Magnetic Resonance Imaging (MRI) is crucial for distinguishing K. kingae from Gram-positive cocci in osteoarticular infections.

Findings:

  • Cartilaginous involvement and modest soft tissue/bone reactions on MRI suggest K. kingae.
  • The subtle presentation of K. kingae necessitates its inclusion in the differential diagnosis for pediatric osteoarticular infections.
  • This report details an unusual case of osteomyelitis with clinical and MRI findings suggestive of K. kingae.

Implications:

  • Recognizing the subtle presentation of Kingella kingae is vital for timely diagnosis and treatment of pediatric septic arthritis.
  • Advanced imaging like MRI plays a key role in differentiating K. kingae from other pathogens in children.
  • This highlights the importance of considering emerging pathogens in the differential diagnosis of pediatric bone and joint infections.

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