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[Osteomyelitis: a probable, uncommon etiology agent].

F Cuoco1, I Borzani, M Torcoletti

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Kingella kingae is an emerging cause of septic arthritis in young children, often presenting subtly. Early MRI can help differentiate K. kingae from other bacterial infections in pediatric osteoarticular cases.

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Area of Science:

  • Pediatric Rheumatology
  • Pediatric Infectious Diseases
  • Pediatric Orthopedic Infections

Background:

  • Septic arthritis accounts for 6.5% of childhood arthritides, often arising from hematogenous spread or direct extension of infection.
  • Commonly implicated bacteria include Staphylococcus aureus and streptococci, but Kingella kingae is increasingly recognized in children under four.
  • Systemic signs like fever and bone pain, alongside local tenderness, often indicate septic arthritis.

Observation:

  • Kingella kingae infections in children typically present with subtle clinical signs and mild inflammatory responses.
  • Affected children may exhibit few overt signs of osteoarticular infection, complicating diagnosis.
  • Early Magnetic Resonance Imaging (MRI) is crucial for distinguishing K. kingae from Gram-positive cocci in osteoarticular infections.

Findings:

  • Cartilaginous involvement and modest soft tissue/bone reactions on MRI suggest K. kingae.
  • The subtle presentation of K. kingae necessitates its inclusion in the differential diagnosis for pediatric osteoarticular infections.
  • This report details an unusual case of osteomyelitis with clinical and MRI findings suggestive of K. kingae.

Implications:

  • Recognizing the subtle presentation of Kingella kingae is vital for timely diagnosis and treatment of pediatric septic arthritis.
  • Advanced imaging like MRI plays a key role in differentiating K. kingae from other pathogens in children.
  • This highlights the importance of considering emerging pathogens in the differential diagnosis of pediatric bone and joint infections.