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[Primary intracranial T cell type malignant lymphoma: a case report]
1Department of Neurosurgery, Kagawa Rosai Hospital, Marugame, Japan.
No Shinkei Geka. Neurological Surgery
|November 1, 1989
Summary
Primary intracranial T cell lymphoma, a rare brain malignancy, was successfully treated with radiation. This case report highlights the effectiveness of 60 Gy irradiation in resolving the tumor, showing no CT differences compared to B cell lymphomas.
Area of Science:
- Neurology
- Oncology
- Pathology
Background:
- Primary intracranial T cell lymphoma is an exceptionally rare form of non-Hodgkin lymphoma.
- Fewer than ten cases have been documented in medical literature.
- This report details an additional case to expand understanding of this rare condition.
Observation:
- A 41-year-old male presented with behavioral changes.
- Enhanced CT scans revealed a high-density mass with surrounding low-density areas in the right frontal lobe, basal ganglia, and periventricular regions.
- Immunohistochemical analysis of a biopsy specimen confirmed diffuse medium T cell lymphoma, with specific marker reactivity (LCA, MT-1, OKT-4, OKT-8).
Findings:
- The patient was diagnosed with diffuse medium T cell type malignant lymphoma.
- Following surgical debulking and 60 Gy of radiation therapy, the intracranial tumor resolved completely.
- CT findings did not differentiate between T cell and B cell types of intracranial lymphoma.
Implications:
- This case underscores the potential efficacy of radiation therapy in treating rare primary intracranial T cell lymphomas.
- The findings suggest that imaging characteristics on CT may not distinguish between T cell and B cell intracranial lymphomas.
- Further research into rare T cell lymphomas is warranted to improve diagnostic and therapeutic strategies.