Related Experiment Video
Updated: Apr 13, 2026
Testing Targeted Therapies in Cancer using Structural DNA Alteration Analysis and Patient-Derived Xenografts
Published on: July 25, 2020
[Recommendation for genetic testing in patients suffering from gynecological malignancy]
Objective:
To present an overview of indications and recommendations for genetic testing in patients with hereditary susceptibility to develop malignant gynecological tumors.
Subject:
Review.
Setting:
Gynecological Oncology Center, Department of Obstetrics and Gynecology, Charles University, First Faculty of Medicine and General Faculty Hospital, Prague.
Subject And Method:
Literature review and recommendations for practice based on evidence and clinical experience.
Conclusion:
Women with hereditary susceptibility to malignant gynecological tumors represent only a relatively small part of the population. However, it is a well-defined risk factor and set of preventive and prophylactic measures can minimize the risk of cancer development (or risk of death from tumor). Knowledge of the indications for genetic testing is one of the basic knowledge of every gynecologist.
