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[A particular type of self management of asthma in childhood. The Neapolis project]
1I Divisione pediatria, Ospedale Santobono, Napoli, Italia.
Insights
Dietary and environmental allergen control significantly improved asthma symptoms in children. Excluding food allergens or house dust mites led to better outcomes than the control group.
Area of Science:
- Pediatric Allergy and Immunology
- Respiratory Medicine
- Clinical Nutrition
Context:
- Asthma management in children often involves identifying and controlling triggers.
- Allergenic triggers can include both environmental factors (aeroallergens) and dietary components (food allergens).
- Current management strategies vary in their approach to allergen elimination and reintroduction.
Purpose:
- To evaluate the impact of different allergen control strategies on pediatric asthma.
- To compare the effectiveness of food allergen exclusion, aeroallergen removal, and combined approaches.
- To assess the role of daily Peak Expiratory Flow (PEF) monitoring versus weekly functional respiratory capacity tests.
Summary:
- Five groups of asthmatic children were studied: Group A (allergic, food exclusion), Group 1B (food exclusion with reintroduction), Group 1C (allergic, no exclusion - control), Group 2A (aeroallergen-only, mite removal), and Group 2B (food-allergen-only, exclusion).
- Asthma pathology was lowest in Group 2B (food allergen exclusion), followed by Group 1A (food exclusion), Group 2A (mite removal), and Group 1B (food exclusion with reintroduction).
- The control group (1C) exhibited severe asthma, requiring significant medication (beta-2-agonists and corticosteroids).
Impact:
- Dietary allergen elimination demonstrates significant benefits for children with food-triggered asthma.
- Environmental allergen control (e.g., mite removal) also shows positive effects on asthma control.
- These findings support tailored allergen management strategies for improving pediatric asthma outcomes.
Abstract:
The goal of this study was the observations of the comportment of 5 groups of asthmatic children, followed either with weekly ambulatory control of functional respiratory capacity or with daily control of PEF at home by Asses Peak Flow. The five groups were formed: group A (10 allergic subjects either to aeroallergens or to foods, with exclusion of food allergens from diet); group 1B (similar group, which executed the food allergen's exclusion with weekly reintroduction of one food allergen with protection of DSCG); group 1C (allergic children either to aeroallergens or to food, who non executed the withdrawal of food allergens from diet: Control group); 2A group (allergic children only to aeroallergens, which executed only the acarus' removal from ambient); 2B group (allergic only to foods, which executed the removal of food allergens from diet). The control's results showed near to 0, for pathology, the group 2B, then the group 1A, then 2A and 1B; the 1C group showed heavy asthmatic condition and employed beta 2-drugs and cortisonics.