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Updated: Apr 13, 2026

Quantitative Magnetic Resonance Imaging of Skeletal Muscle Disease
Published on: December 18, 2016
Utilization of a balanced steady state free precession signal model for improved fat/water decomposition
Leah C Henze Bancroft1, Roberta M Strigel1,2,3, Diego Hernando4
1University of Wisconsin-Madison, Department of Medical Physics, Wisconsin Institutes for Medical Research, Madison, Wisconsin, USA.
Purpose:
Chemical shift based fat/water decomposition methods such as IDEAL are frequently used in challenging imaging environments with large B0 inhomogeneity. However, they do not account for the signal modulations introduced by a balanced steady state free precession (bSSFP) acquisition. Here we demonstrate improved performance when the bSSFP frequency response is properly incorporated into the multipeak spectral fat model used in the decomposition process.
Theory And Methods:
Balanced SSFP allows for rapid imaging but also introduces a characteristic frequency response featuring periodic nulls and pass bands. Fat spectral components in adjacent pass bands will experience bulk phase offsets and magnitude modulations that change the expected constructive and destructive interference between the fat spectral components. A bSSFP signal model was incorporated into the fat/water decomposition process and used to generate images of a fat phantom, and bilateral breast and knee images in four normal volunteers at 1.5 Tesla.
Results:
Incorporation of the bSSFP signal model into the decomposition process improved the performance of the fat/water decomposition.
Conclusion:
Incorporation of this model allows rapid bSSFP imaging sequences to use robust fat/water decomposition methods such as IDEAL. While only one set of imaging parameters were presented, the method is compatible with any field strength or repetition time.
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