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Sample Handling

Sample Handling

Transportation of samples from the collection point to the laboratory, as well as storage and preservation techniques, are crucial for maintaining sample integrity and ensuring accurate and reliable test results.
Samples should be transported carefully from collection points to the laboratory. They should be properly sealed and clearly labeled to prevent cross-contamination. To preserve the sample integrity, optimal temperature conditions during transport are essential. This could involve using...

Preparation of Samples for Electron Microscopy

Preparation of Samples for Electron Microscopy

To be visualized by an electron microscope, either transmission or scanning, biological samples need to be fixed (stabilized) so the electron beam does not destroy them and dried thoroughly (desiccated/dehydrated) so the vacuum does not affect them. Fixation needs to be done as quickly as possible because the sample properties will start changing as soon as it is removed from its natural environment. For example, in a tissue sample, the oxygen levels begin decreasing, causing an altered...

Fixation and Sectioning

Fixation and Sectioning

Two basic types of preparation are used to visualize specimens with a light microscope: wet mounts and fixed specimens.
The simplest type of preparation is the wet mount, in which the specimen is placed in a drop of liquid on the slide. A liquid specimen can be directly deposited on the slide using a dropper. Solid specimens, such as skin scraping, can be placed on the slide before adding a drop of liquid to prepare the wet mount. Sometimes the liquid is simply water, but stains are often added...

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Related Experiment Video

Updated: Apr 12, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Back to basics: specimen management.

Sharon A Van Wicklin

|May 7, 2015

Summary

This summary is machine-generated.

Accurate specimen management is crucial for patient safety and requires clear communication and attention to detail. Adhering to best practices prevents errors that can lead to misdiagnoses and patient harm.

Keywords:

distractions error multidisciplinary communication specimen handling specimen management

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Last Updated: Apr 12, 2026

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Biobank for Translational Medicine: Standard Operating Procedures for Optimal Sample Management

Published on: November 30, 2022

Biobanking of Human Aqueous and Vitreous Liquid Biopsies for Molecular Analyses

Biobanking of Human Aqueous and Vitreous Liquid Biopsies for Molecular Analyses

Published on: September 11, 2023

Establishment of a Clinic-based Biorepository

Establishment of a Clinic-based Biorepository

Published on: May 29, 2017

Area of Science:

Surgical Nursing
Patient Safety
Healthcare Management

Background:

Effective specimen management is vital in perioperative settings.
Standardized processes are essential despite variations in specific actions.

Observation:

Accurate specimen handling demands multidisciplinary communication.
Minimizing distractions and recognizing potential error points are critical.

Findings:

Adherence to best practices by perioperative nurses is key.
Preventing specimen-related errors safeguards against diagnostic inaccuracies and patient harm.

Implications:

Improved specimen management enhances diagnostic accuracy.
Reduced errors protect patients from physical and psychological injury.
Standardized protocols support a safer perioperative environment.