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Related Experiment Videos

Shingles in general practice.

T Peto

    The Practitioner
    |March 22, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Simple shingles patients over 50 benefit from topical idoxuridine or intravenous acyclovir to prevent post-herpetic neuralgia. Younger patients or those with complications/immunosuppression require high-dose intravenous acyclovir.

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    Area of Science:

    • Virology
    • Dermatology
    • Infectious Diseases

    Background:

    • Herpes zoster, commonly known as shingles, is a viral infection.
    • Post-herpetic neuralgia (PHN) is a common and debilitating complication of shingles.

    Purpose of the Study:

    • To outline treatment recommendations for shingles.
    • To differentiate treatment strategies based on patient age and immune status.

    Main Methods:

    • Review of clinical guidelines and evidence for antiviral therapy in shingles.
    • Analysis of treatment efficacy in preventing post-herpetic neuralgia.

    Main Results:

    • Topical idoxuridine or intravenous acyclovir are recommended for patients over 50 with simple shingles to reduce PHN risk.

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  • High-dose intravenous acyclovir is reserved for younger patients with complications or those who are immunosuppressed.

    • Conclusions:

    • Antiviral treatment for shingles should be tailored to patient age and immune status.
    • Early intervention with appropriate antivirals can mitigate the risk of chronic complications like PHN.