Related Experiment Video

Updated: Apr 12, 2026

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery
08:17

Murine Echocardiography of Left Atrium, Aorta, and Pulmonary Artery

Published on: February 20, 2017

15.2K

[Left ventricular hypertrophy as a marker of adverse cardiovascular risk in persons of various age groups]

A V Barsukov, D V Glukhovskoĭ, M P Zobnina

    Advances in Gerontology = Uspekhi Gerontologii
    |May 8, 2015
    PubMed

    Insights

    Left ventricular hypertrophy (LVH) in elderly hypertensive patients is complex. Myocardial mass is a key prognostic factor, alongside type of LVH, atrial dilatation, and metabolic syndrome, influencing long-term outcomes.

    Area of Science:

    • Cardiology
    • Internal Medicine
    • Hypertension Research

    Background:

    • Left ventricular hypertrophy (LVH) is a significant cardiovascular condition.
    • Understanding the prognostic value of different LVH types is crucial for patient management.
    • Hypertension, metabolic syndrome, and obesity contribute to cardiac structural changes.

    Purpose of the Study:

    • To analyze the prognostic significance of various types of left ventricular hypertrophy (LVH).
    • To investigate the interplay of demographic, hemodynamic, and regulatory factors in LVH prognosis.
    • To evaluate the role of left atrial dilatation and metabolic disorders in essential hypertension outcomes.

    Main Methods:

    • Review of modern conceptions on LVH prognosis.
    • Analysis of own investigations in elderly hypertensive patients.
    • Assessment of left ventricular myocardial mass, geometry, and left atrial size.
    • Evaluation of metabolic disorders and abdominal obesity impact.

    Main Results:

    • Left ventricular myocardial mass is as important as LVH type (concentric/eccentric) for long-term prognostication in elderly hypertensive patients.
    • Left atrial dilatation is an integral part of the cardiovascular continuum in essential hypertension.
    • Metabolic disorders associated with hypertension and abdominal obesity contribute to cardiac structural and functional issues.

    Conclusions:

    • Left ventricular myocardial mass is a critical prognostic indicator in elderly hypertensive patients with LVH.
    • Left atrial dilatation and metabolic syndrome significantly impact cardiovascular outcomes in hypertension.
    • Tailoring prognostication and management based on LVH type, myocardial mass, and metabolic status is essential.

    More Related Videos

    Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension10:03

    Evaluation of Right Ventricular Function in Experimental Models of Pulmonary Arterial Hypertension

    Published on: June 27, 2025

    992
    A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure07:13

    A Rat Model of Pressure Overload Induced Moderate Remodeling and Systolic Dysfunction as Opposed to Overt Systolic Heart Failure

    Published on: April 30, 2020

    7.0K

    Related Concept Videos

    Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

    Cardiomyopathy III: Hypertrophic Cardiomyopathy

    Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
    767
    Heart Failure II: Pathophysiology01:29

    Heart Failure II: Pathophysiology

    Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
    1.5K
    Mitral Regurgitation I: Introduction01:20

    Mitral Regurgitation I: Introduction

    Mitral regurgitation is characterized by the backward circulation of blood from the left ventricle to the left atrium during systole, a phase of the cardiac cycle when the heart contracts and pumps blood out of the chambers. This abnormal flow occurs primarily due to the dysfunction of the mitral valve or its supporting structures, which include the mitral leaflets, chordae tendineae, annulus, and papillary muscles.Etiology and Mechanisms:Primary Mitral Regurgitation: This type arises from...
    1.1K
    Pathophysiology of Heart Failure01:17

    Pathophysiology of Heart Failure

    Heart failure (HF) is a progressive syndrome involving ventricles that leads to inadequate cardiac output. It can be classified based on location and output or ejection fraction. Ejection fraction (EF) is an essential measurement in the diagnosis and surveillance of HF. Reduced EF corresponds to systolic heart failure (HFrEF). However, HF with preserved ejection fraction (HFpEF) is becoming increasingly prevalent. Also known as diastolic HF, this form of HF is related to aging. The...
    4.7K
    Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers01:19

    Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers

    Cardiac biomarkers are critical in diagnosing, prognosing, and managing cardiovascular diseases. Routine measurement of specific biomarkers such as B-type natriuretic peptide (BNP), C-reactive protein (CRP), and homocysteine (Hcy) is common practice in clinical settings to evaluate heart function and predict cardiovascular events.
    These markers indicate stress or strain on the heart muscle:
    Natriuretic Peptides (BNP)
    Cardiac myocytes produce these hormones in response to ventricular stretching...
    781
    Heart Failure I: Introduction01:27

    Heart Failure I: Introduction

    Heart failure refers to a clinical syndrome caused by structural or functional cardiac disorders that prevent the heart from pumping an adequate amount of blood to meet the body's metabolic needs. This condition often arises from myocardial infarction or ischemia, leading to decreased cardiac output, reduced tissue perfusion, impaired gas exchange, fluid volume imbalance, and decreased functional ability.Heart failure can result from disruptions in the mechanisms that regulate cardiac output...
    1.3K