DRAPA trial--closed-suction drains versus closed gravity drains in pancreatic surgery: study protocol for a...

Area of Science:

• Surgical Oncology
• Gastroenterology
• Clinical Trials

Background:

• Pancreatic resection has high morbidity, primarily due to pancreatic fistulae.
• Intraabdominal drains are crucial post-surgery, but optimal drain type remains unclear.
• Closed-suction drains offer effective fluid removal but raise concerns about fistula risk.

Purpose of the Study:

• To compare closed-suction drains versus closed passive gravity drains in pancreatic resection.
• To determine the most suitable drain type for minimizing postoperative pancreatic fistulae.
• To evaluate the impact of drain type on overall postoperative morbidity.

Main Methods:

• The DRAins in PAncreatic surgery (DRAPA) trial is a dual-centre, prospective, randomized controlled trial.
• Participants undergoing pancreatic resection will be randomized to either closed-suction or closed passive gravity drainage.
• Primary endpoint: rate of postoperative pancreatic fistula; Secondary endpoint: postoperative morbidity (3-month follow-up).

Main Results:

• This section is not applicable as the abstract does not contain results.
• This section is not applicable as the abstract does not contain results.
• This section is not applicable as the abstract does not contain results.

Conclusions:

• No prior studies have directly compared different drain types in pancreatic surgery.
• This trial aims to provide evidence-based guidance on drain selection.
• The study seeks to reduce pancreatic fistula rates and improve patient outcomes.