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Corneal thickness, epithelial thickness and axial length differences in normal and high myopia
Xiaogang Wang1, Jing Dong2, Qiang Wu3
1Shanxi Eye Hospital, Shanxi, P.R. China. movie6521@163.com.
BMC Ophthalmology
|May 8, 2015
Summary
High myopia (HM) is linked to thicker corneal thickness (CT) but not epithelial thickness (ET). Axial length (AL), CT, and ET are influenced by age and gender in both normal and HM individuals.
Area of Science:
- Ophthalmology
- Corneal Imaging
- Myopia Research
Background:
- High myopia (HM) may impact corneal biometric parameters, but its effects on corneal thickness (CT) and epithelial thickness (ET) require further clarification.
- Understanding these influences is crucial for managing HM and its ocular complications.
Purpose of the Study:
- To compare ET, CT, and axial length (AL) between normal and HM subjects.
- To investigate the influence of age and gender on these corneal parameters and AL in both groups.
Main Methods:
- A cross-sectional study included 97 normal subjects and 48 HM subjects.
- Corneal ET and CT were measured across 17 regions within a 6-mm diameter, alongside AL data acquisition.
Main Results:
- HM subjects exhibited significantly increased AL (approx. 4 mm) and thicker CT in most regions, while ET showed no significant difference.
- In normal subjects, age negatively correlated with AL; gender correlated with ET. In HM subjects, age did not correlate with CT, AL, or ET, but gender correlated with AL and CT.
Conclusions:
- Corneal thickness (CT) is greater in high myopia (HM) individuals, whereas epithelial thickness (ET) is not significantly different.
- Age and gender are important factors to consider when analyzing AL, CT, and ET in both normal and HM populations.
