Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Motivation seen through the kaleidoscope of multi-disciplinarity and multi-scales: towards the emergence of new paradigms and perspectives favored by crossed looks.

Frontiers in behavioral neuroscience·2025
Same author

Circadian and Age-Related Variations of Amino Acids Levels in <i>Drosophila</i> Brains: Correlations and Descriptive Dimensions.

ACS chemical neuroscience·2025
Same author

MOG antibody non-P42 epitope is associated with a higher risk of relapse in paediatric MOGAD.

Journal of neurology, neurosurgery, and psychiatry·2025
Same author

Neurochemical Assessment of Tissue Levels of Neurotransmitters for Approximating Neurotransmitter System Connectivity.

ACS chemical neuroscience·2025
Same author

Do Neurochemicals Reflect Psychophysiological Dimensions in Behaviors? A Transdisciplinary Perspective Based on Analogy with Maslow's Needs Pyramid.

ACS chemical neuroscience·2025
Same author

Neurochemical Databases: Purpose and Expectations.

ACS chemical neuroscience·2024

Related Experiment Video

Updated: Apr 12, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.1K

Why Optogenetics Needs in Vivo Neurochemistry.

Sandrine Parrot1, Luc Denoroy2, Bernard Renaud1,3

  • 1†INSERM U1028; CNRS UMR5292; Université Lyon 1; Lyon Neuroscience Research Center, NeuroDialyTics Unit, Lyon, F-69000, France.

ACS Chemical Neuroscience
|May 8, 2015
PubMed
Summary

Neurochemical optogenetics, studying light-induced brain changes, lacks in vivo neurochemical data. Unknown factors may hinder this emerging neuroscience field despite advanced analytical tools.

Keywords:
Optogeneticsin vivo neurochemistrymicrodialysisneurotransmittersvoltammetry

More Related Videos

Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
11:31

Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex

Published on: February 25, 2022

3.0K
In Vivo Wide-Field and Two-Photon Calcium Imaging from a Mouse Using a Large Cranial Window
06:45

In Vivo Wide-Field and Two-Photon Calcium Imaging from a Mouse Using a Large Cranial Window

Published on: August 4, 2022

8.9K

Related Experiment Videos

Last Updated: Apr 12, 2026

In vivo Optogenetic Stimulation of the Rodent Central Nervous System
09:37

In vivo Optogenetic Stimulation of the Rodent Central Nervous System

Published on: January 15, 2015

61.1K
Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex
11:31

Ex Vivo Optogenetic Interrogation of Long-Range Synaptic Transmission and Plasticity from Medial Prefrontal Cortex to Lateral Entorhinal Cortex

Published on: February 25, 2022

3.0K
In Vivo Wide-Field and Two-Photon Calcium Imaging from a Mouse Using a Large Cranial Window
06:45

In Vivo Wide-Field and Two-Photon Calcium Imaging from a Mouse Using a Large Cranial Window

Published on: August 4, 2022

8.9K

Area of Science:

  • Neuroscience
  • Optogenetics
  • Neurochemistry

Background:

  • Optogenetic manipulation is commonly assessed via in vivo electrophysiology and behavioral changes in rodents.
  • In vivo neurochemical effects of optogenetic stimulation are underreported, despite advancements in analytical techniques.

Purpose of the Study:

  • To highlight the scarcity of in vivo neurochemical data in optogenetics research.
  • To identify potential reasons for the lack of development in "neurochemical optogenetics".

Main Methods:

  • Literature review and analysis of current research trends in optogenetics and neurochemistry.
  • Identification of knowledge gaps regarding in vivo neurochemical monitoring during optogenetic stimulation.

Main Results:

  • A significant disparity exists between the study of optogenetic effects on neural activity/behavior and neurochemical changes.
  • Existing analytical techniques for monitoring neurotransmitters are not widely applied in the context of in vivo optogenetic studies.

Conclusions:

  • Unknown or poorly understood factors are likely impeding the growth of "neurochemical optogenetics".
  • Further research is needed to bridge the gap between optogenetic manipulation and in vivo neurochemical analysis.