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Related Experiment Video

Updated: Apr 12, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

Published on: March 15, 2019

Postexercise hypotension after maximal short-term incremental exercise depends on exercise modality.

Felipe A Cunha¹, Adrian W Midgley, Pedro P Soares

¹Medical Sciences Graduate Program, Faculty of Medical Sciences, University of Rio de Janeiro State, Rio de Janeiro, Brazil., Physical Activity and Health Promotion Laboratory, University of Rio de Janeiro State, Rio de Janeiro, Brazil.

Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme

|May 8, 2015

Summary

Exercise mode significantly impacts postexercise hypotension (PEH) in healthy men. Running elicits greater PEH, primarily driven by reduced systemic vascular resistance and increased sympatho-vagal balance.

Keywords:

cardiovascular physiology energy expenditure ergometry ergométrie heart rate variability la physiologie cardiovasculaire la sensibilité baroréflexe spontanée la variabilité de la fréquence cardiaque les dépenses d’énergie spontaneous baroreflex sensitivity

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Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

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Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

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Last Updated: Apr 12, 2026

Supramaximal Intensity Hypoxic Exercise and Vascular Function Assessment in Mice

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Published on: March 15, 2019

Conducting Maximal and Submaximal Endurance Exercise Testing to Measure Physiological and Biological Responses to Acute Exercise in Humans

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Published on: October 17, 2018

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Impact of High-intensity Interval Exercise and Moderate-Intensity Continuous Exercise on the Cardiac Troponin T Level at an Early Stage of Training

Published on: October 10, 2019

Area of Science:

Cardiovascular Physiology
Exercise Science
Autonomic Neuroscience

Background:

Postexercise hypotension (PEH) is a phenomenon of reduced blood pressure following exercise.
The influence of different exercise modalities on PEH magnitude and underlying physiological mechanisms remains incompletely understood.

Purpose of the Study:

To investigate the effects of maximal cardiopulmonary exercise testing (CPET) via cycling, walking, and running on PEH.
To identify the determinants of PEH, including systemic vascular resistance (SVR) and autonomic function.

Main Methods:

Twenty healthy men underwent three maximal CPETs (cycling, walking, running) in a randomized order.
Measurements included blood pressure, heart rate, cardiac output, SVR, spontaneous baroreflex sensitivity (BRS), and heart rate variability (HRV) for 60 minutes post-exercise.
Total exercise volume (energy expenditure during CPET plus recovery) was calculated.

Main Results:

Total exercise volume was highest during running CPET.
Significant PEH, characterized by reduced systolic blood pressure, was observed only after running CPET.
Post-exercise, heart rate and cardiac output increased, while SVR decreased across all modalities.
BRS and HRV decreased, and sympatho-vagal balance (LF:HF ratio) increased, particularly after running.
Changes in SVR, BRS, and sympathetic activity correlated with blood pressure variations.

Conclusions:

Exercise mode and total exercise volume are key determinants of PEH magnitude in healthy men.
Running-induced PEH is primarily linked to decreased SVR and heightened sympatho-vagal balance, potentially a reflex response to peripheral vasodilation.