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Related Concept Videos

Redox Reactions01:24

Redox Reactions

59.5K
Oxidation-reduction or redox reactions involve the transfer of electrons from one molecule or atom to another. When an atom gains an electron, another atom must lose an electron, meaning oxidation and reduction must occur together. Since the redox occurs in pairs, the atom that gets oxidized is also called the reducing agent or reductant, and the atom that is reduced is also called the oxidizing agent or oxidant. A straightforward way to remember the definitions of oxidation and reduction is...
59.5K
Redox Reactions01:27

Redox Reactions

1.4K
Redox reactions are vital biochemical processes that underpin energy metabolism in cells. These reactions involve the transfer of electrons between molecules, occurring in tandem as oxidation and reduction. Oxidation refers to the loss of electrons, while reduction denotes their gain. This coupling ensures the seamless flow of electrons through metabolic pathways. For example, in bacterial metabolism, glucose undergoes oxidation to carbon dioxide, while oxygen is simultaneously reduced to...
1.4K

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Related Experiment Video

Updated: Apr 12, 2026

Live Imaging of the Mitochondrial Glutathione Redox State in Primary Neurons using a Ratiometric Indicator
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Live Imaging of the Mitochondrial Glutathione Redox State in Primary Neurons using a Ratiometric Indicator

Published on: October 20, 2021

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[Redox Molecular Imaging Using ReMI].

Fuminori Hyodo1, Shinji Ito, Hideo Utsumi

  • 1Innovation Center for Medical Redox Navigation, Kyushu University.

Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan
|May 8, 2015
PubMed
Summary
This summary is machine-generated.

Monitoring tissue redox status is crucial for health. Magnetic resonance imaging (MRI) and dynamic nuclear polarization-MRI (DNP-MRI) offer promising in vivo redox molecular imaging (ReMI) for diagnosing diseases and assessing treatments.

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Cellular Redox Profiling Using High-content Microscopy
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Cellular Redox Profiling Using High-content Microscopy
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Cellular Redox Profiling Using High-content Microscopy

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Area of Science:

  • Biochemistry
  • Physiology
  • Medical Imaging

Context:

  • Tissue redox status is vital for maintaining homeostasis and cellular functions, including energy production.
  • Imbalances in redox status, involving molecules like reactive oxygen species and glutathione, can lead to oxidative stress and diseases such as cancer, neurological disorders, and aging.
  • Monitoring antioxidant levels and tissue redox status is essential for disease diagnosis and evaluating treatment efficacy.

Purpose:

  • This review explores the application of magnetic resonance technologies for imaging tissue redox status.
  • It specifically focuses on magnetic resonance imaging (MRI) and dynamic nuclear polarization-MRI (DNP-MRI) in conjunction with redox-sensitive contrast agents.

Summary:

  • Redox reactions are fundamental to metabolic processes, and their balance is critical for cellular health.
  • Breakdown of this balance contributes to various pathologies, highlighting the need for effective monitoring tools.
  • In vivo redox molecular imaging (ReMI) technologies, including ESRI, MRI, and DNP-MRI, are emerging as powerful modalities for assessing tissue redox status.

Impact:

  • In vivo redox molecular imaging using MRI and DNP-MRI provides a non-invasive method to visualize and quantify tissue redox status.
  • This technology can aid in the early diagnosis of diseases linked to redox imbalance.
  • It also offers a means to monitor therapeutic responses in conditions affected by oxidative stress.