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Multidrug-resistant Nocardia pseudobrasiliensis presenting as multiple muscle abscesses
Vimalkumar Veerappan Kandasamy1, Arun Nagabandi1, Edward A Horowitz2
1Department of Internal Medicine, Creighton University, Omaha, Nebraska, USA.
BMJ Case Reports
|May 8, 2015
Summary
Nocardia pseudobrasiliensis causes rare leg abscesses, particularly in immunocompromised patients. Distinguishing it from Nocardia brasiliensis is crucial due to differing antibiotic responses and disease severity.
Area of Science:
- Medical Microbiology
- Infectious Diseases
Background:
- Nocardia pseudobrasiliensis is an emerging pathogen.
- Chronic steroid use for myasthenia gravis can increase susceptibility to Nocardia infections.
Observation:
- A 79-year-old male on chronic steroid therapy presented with multiple leg abscesses.
Findings:
- The patient was diagnosed with Nocardia pseudobrasiliensis infection.
- This species was previously misidentified as Nocardia brasiliensis.
- N. pseudobrasiliensis exhibits distinct antibiotic susceptibility and is associated with more severe, disseminated disease.
Implications:
- Accurate identification of Nocardia pseudobrasiliensis is critical for effective treatment.
- Increased awareness of this emerging species is needed in clinical practice.
- Understanding the distinct pathogenic potential of N. pseudobrasiliensis is vital for patient management.
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