Perioperative chlorhexidine allergy: Is it serious?

Area of Science:

• Medical microbiology
• Clinical immunology
• Patient safety

Background:

• Chlorhexidine is a widely utilized antiseptic with potent antimicrobial efficacy.
• Its use spans various medical preparations and applications.
• However, chlorhexidine is recognized as a potential allergen.

Purpose of the Study:

• To review current evidence on allergic reactions to chlorhexidine.
• To focus on reactions associated with surgical and interventional procedures.
• To consolidate knowledge on chlorhexidine allergy in clinical practice.

Main Methods:

• Literature review of evidence-based studies.
• Analysis of reported allergic reactions to chlorhexidine.
• Focus on peri-procedural contexts.

Main Results:

• Chlorhexidine, despite its benefits, can elicit allergic responses.
• Adverse reactions are documented in surgical and interventional settings.
• Understanding these reactions is crucial for patient safety.

Conclusions:

• Allergic reactions to chlorhexidine are a significant consideration.
• Healthcare providers should be aware of this potential adverse effect.
• Further vigilance is needed during procedures involving chlorhexidine.