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Related Experiment Video

Updated: Apr 12, 2026

Visualizing Field Data Collection Procedures of Exposure and Biomarker Assessments for the Household Air Pollution Intervention Network Trial in India
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The EVEREST study: an international collaboration.

Fergus J Caskey, Vianda S Stel1, Robert F Elliott2

  • 1ERA-EDTA Registry, Department of Medical Informatics, Academic Medical Center , Amsterdam , The Netherlands.

NDT Plus
|May 8, 2015
PubMed
Summary
This summary is machine-generated.

Global renal replacement therapy (RRT) use and outcomes vary widely. The EVEREST study analyzed medical and non-medical factors across 46 countries to understand RRT incidence, treatment choices, and survival rates.

Keywords:
dialysisepidemiology and outcomesrisk factors

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Area of Science:

  • Nephrology
  • Epidemiology
  • Health Services Research

Background:

  • Significant international variation exists in renal replacement therapy (RRT) initiation, home dialysis use, and patient outcomes.
  • Understanding the drivers of this heterogeneity is crucial for improving global kidney disease care.

Purpose of the Study:

  • To investigate the association between medical and non-medical factors and RRT incidence, modality mix, and survival.
  • To describe the baseline characteristics of countries participating in the EVEREST study.

Main Methods:

  • Collected incident and prevalent RRT patient data across multiple time periods (1983-2005).
  • Gathered general population health indicators and national macroeconomic data.
  • Obtained primary data on renal service funding, resources, and organization from national experts.

Main Results:

  • Median RRT incidence was 130 per million population.
  • Life expectancy at 60 averaged 22.1 years; 6.9% of the population had diabetes.
  • Healthcare spending was 8.1% of GDP, with 9 dialysis facilities per million population, mostly publicly or non-profit owned.

Conclusions:

  • The EVEREST study provides a comprehensive dataset on RRT epidemiology and healthcare system characteristics.
  • The wide heterogeneity among participating countries allows for robust modeling to identify factors influencing RRT outcomes.