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A comparison of contractile function in large and small pulmonary arterial vessels of the rat
R M Leach1, C H Twort, I R Cameron
1Department of Medicine, United Medical School, London.
Quarterly Journal of Experimental Physiology (Cambridge, England)
|November 1, 1989
Abstract:
The contractile function of rat pulmonary arterial vessels, ranging in internal diameter from 100 to 2000 microns, was studied in vitro using a small vessel myograph. It was found that vessels with a diameter of 200-400 microns produced considerably more force for a given intervention than those either smaller (less than 100-2000 microns) or larger (400-2000 microns). It is suggested that these vessels may play an important role in the generation of pulmonary vascular resistance.