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Related Experiment Videos

Zinc in the elderly.

A Senapati1, G Jenner, R P Thompson

  • 1Gastrointestinal Laboratory, Rayne Institute, London.

The Quarterly Journal of Medicine
|January 1, 1989
PubMed
Summary
This summary is machine-generated.

Elderly patients in hospital showed lower zinc levels, but this was not linked to skin ulcers. Poor dietary zinc intake may contribute to low tissue zinc in these patients.

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Area of Science:

  • Gerontology
  • Nutritional Science
  • Dermatology

Background:

  • Elderly individuals, particularly those in hospital settings, may be at risk for nutritional deficiencies.
  • Cutaneous ulcers are a common concern in elderly populations, with multifactorial causes.
  • Zinc is an essential trace element involved in immune function and tissue repair.

Purpose of the Study:

  • To investigate plasma and leucocyte zinc levels in elderly patients with and without cutaneous ulcers.
  • To compare zinc status in hospitalized elderly patients with healthy community-dwelling elderly and younger individuals.
  • To explore the potential association between zinc levels, hospitalization, and the development of cutaneous ulcers.

Main Methods:

  • Comparative analysis of plasma and leucocyte zinc concentrations.

Related Experiment Videos

  • Assessment of zinc intake relative to recommended daily allowances.
  • Evaluation of tissue zinc levels in different elderly cohorts.

    • Main Results:

    • Hospitalized elderly patients exhibited lower plasma and leucocyte zinc levels compared to healthy controls.
    • These reduced zinc levels in hospitalized patients were not significantly associated with the presence of cutaneous ulcers.
    • Zinc intake in hospitalized patients was considerably below recommended daily allowances.
    • Low tissue zinc levels were observed in elderly patients in hospital, likely due to inadequate intake.

    Conclusions:

    • Low plasma and leucocyte zinc levels are prevalent in elderly patients in hospital, irrespective of cutaneous ulcer status.
    • Inadequate dietary zinc intake appears to be a significant factor contributing to low tissue zinc in hospitalized elderly patients.
    • The direct role of low tissue zinc in the formation of cutaneous ulcers in this population remains unproven.