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Direct reprogramming of induced neural progenitors: a new promising strategy for AD treatment

Siqiang Lai1, Min Zhang1, Dongsheng Xu1,2

  • 1Tenth People's Hospital affiliated to Tongji University School of Medicine, Shanghai, 200072 China.

Translational Neurodegeneration
|May 8, 2015
PubMed

Keywords:
Alzheimer’s diseaseInduced neural progenitor cellsStem cell-based therapy

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Nuclear reprogramming is the process of switching gene expression of one cell type to that of another cell type, usually from a differentiated cell state to an undifferentiated cell state. Differentiation occurs during processes such as development and morphogenesis, tissue regeneration, and malignancy. Cells can also be artificially induced to reprogram their gene expression by techniques such as nuclear transfer, induced pluripotency, and cell fusion. Such techniques have many applications in...
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