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Updated: Feb 8, 2026

Assessment of Sexual Behavior of Male Mice
Published on: March 5, 2020
Nodular hyperplasia of the bartholin gland increasing in size during sexual intercourse
F Tresserra1, P J Grases, M Cararach
1Departments of *Pathology and †Obstetrics and Gynecology, Instituto Universitario Dexeus, Barcelona, Spain.
Objective:
A case of Bartholin gland nodular hyperplasia with review of the literature and diagnostic criteria is reported.
Material And Methods:
In a 31-year-old woman, a nodular mass was found arising in the left labium minus. The mass size increased during sexual intercourse.
Results:
The mass was well-circumscribed but not encapsulated and showed a proliferation of acini lined by mucussecreting columnar epithelium. The lesion retained the lobular pattern and the relationship between acini and ducts as seen in the normal Bartholin gland.
Conclusion:
Nodular hyperplasia of the Bartholin gland should be differentiated from adenoma, in which architecture is disrupted. Variation in size during sexual intercourse probably is mediated by vascular engorgement. Surgical excision is curative.
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