Large-Loop Excision Using a New Probe: Variloop for the Treatment of CIN

Area of Science:

• Gynecology
• Oncology
• Surgical Technology

Background:

• Cervical intraepithelial neoplasia (CIN) requires effective outpatient treatment options.
• The Variloop, a diathermic loop with adjustable diameter, offers a potential solution for CIN management.

Purpose of the Study:

• To evaluate the efficiency and outcomes of using the Variloop for treating CIN in an outpatient setting.
• To assess the impact of the Variloop on histological evaluation and patient follow-up.

Main Methods:

• Loop electrosurgical excision was performed on 185 patients with varying grades of CIN.
• Procedures averaged 10 minutes, with local anesthesia used in most cases.
• Specimens were consistently removed in one piece for analysis.

Main Results:

• Minimal thermal alteration (1%) occurred, not hindering histological evaluation.
• High correlation between biopsy and conization diagnosis was observed, especially for CIN3 (70%).
• 92.4% of cases achieved clear endocervical margins; 1-year follow-up noted minimal stenosis in a few patients.

Conclusions:

• The adjustable Variloop is an efficient method for treating CIN when endocervical development is within 15 mm of the external os.
• The procedure causes minimal thermic alterations, ensuring accurate histological assessment.
• The Variloop demonstrates good efficacy in managing CIN with favorable margin status and minimal complications.