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Orthotopic Small Bowel Transplantation in Rats
Published on: November 6, 2012
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Technical aspects of intestinal transplantation
H Furukawa1, K Abu-Elmagd1, J Reyes1
1Pittsburgh Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
Surgical Technology International
|May 8, 2015
Summary
The potent immunosuppressive agent FK 506 has made intestinal transplantation a viable treatment for irreversible intestinal failure. This chapter details clinical experience and technical aspects of donor and recipient surgeries.
Area of Science:
- Gastroenterology and Hepatology
- Transplantation Surgery
- Immunology
Background:
- Irreversible intestinal failure poses significant challenges.
- The development of potent immunosuppressants like FK 506 has advanced transplantation feasibility.
- Intestinal transplantation offers a therapeutic option for select patients.
Purpose of the Study:
- To present clinical experience in intestinal transplantation.
- To focus on the technical aspects of donor and recipient surgical procedures.
Main Methods:
- Review of clinical cases undergoing intestinal transplantation.
- Detailed description of surgical techniques for donor procurement.
- Detailed description of surgical techniques for recipient operation.
Main Results:
- Intestinal transplantation is a feasible option due to advancements in immunosuppression.
- Successful outcomes depend on meticulous surgical technique.
Conclusions:
- Intestinal transplantation is a viable solution for intestinal failure.
- Technical proficiency in donor and recipient operations is crucial for success.
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