Molecular diagnostic testing in breast cancer

Area of Science:

• Oncology
• Molecular Biology
• Genetics

Background:

• Molecular tests are increasingly vital in modern breast cancer treatment.
• Understanding these tests is essential for effective patient management.

Purpose of the Study:

• To provide a comprehensive overview of molecular tests used in breast cancer treatment.
• To organize these tests by cancer stage and clinical condition.

Main Methods:

• Systematic review of scientific literature.
• Analysis of clinical practice guideline recommendations.
• Inclusion of data from molecular test manufacturers.

Main Results:

• Multiple molecular tests analyzing cancer-related gene expression have been validated.
• These tests are recommended by clinical guidelines for informing diagnosis and treatment.
• Personalized interventions are increasingly guided by molecular test results.

Conclusions:

• Molecular testing is integral to breast cancer patient care.
• Oncology nurses need expertise in prescribing, interpreting, and explaining molecular tests.
• This knowledge empowers nurses to provide optimal patient guidance and support.