Related Experiment Video
Updated: Apr 12, 2026

Precise Visualization of Insulin Receptors A and B in Murine Brain with an RNA In Situ Hybridization Assay
Published on: July 15, 2025
Irisin, an exercise-induced myokine as a metabolic regulator: an updated narrative review
Ning Chen1, Qingxue Li2,3, Jun Liu1
1College of Health Science, Hubei Provincial Collaborative Innovation Center for Exercise and Health Promotion, Wuhan Sports University, Wuhan, China.
Abstract:
Irisin, as a new hormone-like myokine, is discovered in the presence of exercise-induced peroxisome proliferator-activated receptor gamma coactivator-1-alpha (PGC-1α). Which substance plays an important role in energy metabolism in each organ in the body and the regulation of metabolic diseases such as obesity and diabetes. The finding of irisin can contribute to the exploration of the novel and effective therapeutic targets or therapeutic strategies of these metabolic diseases or metabolism-associated health issues. To date, little is known regarding the functions and regulatory mechanisms of irisin with respect to metabolic diseases or metabolism-associated health issues. In this narrative review article, we systematically introduce its structural characteristics, production and distribution in tissues and organs, and the regulation and corresponding mechanisms for metabolic diseases or metabolism-associated health issues of irisin. Meanwhile, its future prospects and the development of irisin-related products for the promotion of human health have also been proposed, which will benefit future research and application of irisin. Copyright © 2015 John Wiley & Sons, Ltd.
More Related Videos
10:59Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy
Published on: May 28, 2021
09:16Real-Time Analysis of Bioenergetics in Primary Human Retinal Pigment Epithelial Cells Using High-Resolution Respirometry
Published on: February 3, 2023
Related Concept Videos
Regulation of the Unfolded Protein Response
Regulation of Metabolism
Insulin: The Receptor and Signaling Pathways
Global Regulatory Systems
Transcriptional Regulation: Riboswitches
Translational Regulation