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Effectiveness and safety of laparoscopic adrenalectomy of large pheochromocytoma: a prospective, nonrandomized,
Weigang Wang1, Ping Li2, Yishu Wang3
1The Second Department of Urology, The First Hospital, Jilin University, 71 Xinmin Street, Changchun 130021, China.
Background:
Laparoscopic adrenalectomy (LA) is normally used to treat small-sized (<6 cm) pheochromocytoma (PCC). This study evaluated the effectiveness and safety of LA for treating large (≥6 cm) PCC.
Methods:
Fifty-one patients with resectable, large-sized (≥6 cm) PCC were prospectively enrolled for elective LA (n = 23) or open adrenalectomy (n = 28).
Results:
LA was converted into open adrenalectomy in 2 patients (2/23, 8.7%); LA was associated with relatively longer operative time (P = .033) but less intraoperative bleeding (P < .001), faster resumption of ambulatory status (P < .001), and shorter duration of postoperative hospitalization (P < .001). Frequency of PCC recurrence was similar between the 2 groups (P = 1.000).
Conclusions:
LA is a feasible, effective, and safe treatment modality for large-sized (≥6 cm) PCC. LA is associated with minimal invasiveness and faster postoperative recovery.
