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Blood pressure after surgery among obese and nonobese children with obstructive sleep apnea
Yen-Lin Kuo1, Kun-Tai Kang2, Shuenn-Nan Chiu3
1Department of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan Department of Otolaryngology, National Taiwan University Hospital, Hsin-chu Branch, Taipei, Taiwan.
Insights
Adenotonsillectomy (T&A) significantly reduces blood pressure in nonobese children with obstructive sleep apnea (OSA). Obese children with OSA show less improvement in blood pressure after T&A surgery.
Area of Science:
- Pediatric Sleep Medicine
- Cardiovascular Health in Children
- Surgical Outcomes
Background:
- Obstructive sleep apnea (OSA) is common in children and linked to cardiovascular issues.
- Adenotonsillectomy (T&A) is a primary treatment for pediatric OSA, often associated with blood pressure reduction.
- The impact of obesity on T&A's effectiveness in improving blood pressure in children with OSA is not well-defined.
Purpose of the Study:
- To investigate the effect of adenotonsillectomy (T&A) on blood pressure in obese versus nonobese children diagnosed with obstructive sleep apnea (OSA).
- To determine if obesity influences the cardiovascular benefits of T&A in pediatric OSA patients.
Main Methods:
- A case series with chart review was conducted at a tertiary referral center.
- 78 children with OSA were included and matched using propensity scores into obese (n=39) and nonobese (n=39) groups.
- Blood pressure was measured preoperatively and within 3 months post-T&A, including nocturnal and morning readings.
Main Results:
- Nonobese children experienced significant reductions in nocturnal diastolic blood pressure (DBP) index and morning systolic blood pressure (SBP) and DBP post-T&A.
- Obese children showed no significant changes in blood pressure parameters after surgery.
- Analysis revealed superior blood pressure improvements in nonobese children compared to obese children following T&A.
Conclusions:
- Nonobese children with OSA demonstrate greater blood pressure improvements after T&A compared to their obese counterparts.
- Obese children with OSA may experience diminished cardiovascular benefits from T&A.
- These findings suggest obesity could be a factor limiting the effectiveness of T&A in managing cardiovascular risks associated with pediatric OSA.
Objectives:
Treating obstructive sleep apnea in children is found to be associated with blood pressure decreases. However, exactly how adenotonsillectomy (T&A) affects blood pressure in obese and nonobese children remains unclear. This study assesses how obesity affects blood pressure in children with sleep apnea after T&A.
Study Design:
Case series with chart review.
Setting:
A tertiary referral center.
Subjects And Methods:
From 2010 to 2012, a total of 78 children were included. Based on propensity score methods (age, sex, and preoperative apnea-hypopnea index matched), children were assigned to either the obese group (n = 39) or the nonobese group (n = 39). All children received adenotonsillectomy. We recorded clinical symptoms, preoperative overnight polysomnography (PSG), and subsequent PSG within 3 months after T&A. We measured blood pressure 3 times before PSG (nocturnal blood pressure) and after PSG (morning blood pressure) in a sleep laboratory.
Results:
Following surgery, the nonobese group had a significantly decreased nocturnal diastolic blood pressure (DBP) index (-12.0 to -18.8, P = .018), morning systolic blood pressure (SBP; 111.1 to 105.8 mm Hg, P = .014), SBP index (-5.4 to -10.9, P = .008), and DBP (-12.0 to -18.7, P = .023). Nevertheless, all blood pressure parameters in the obese group were not significantly changed postoperatively. The nonobese group improved more than obese group in nocturnal and morning DBP and DBP index by 2-way analysis of variance.
Conclusion:
Among the children receiving T&A as treatment for OSA, nonobese children improved more than obese children did in terms of blood pressure, allowing us to infer that obese children with OSA may benefit less from T&A in cardiovascular morbidities.
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