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Updated: Apr 12, 2026

A Flow Cytometry-Based Cytotoxicity Assay for the Assessment of Human NK Cell Activity
Published on: August 9, 2017
Enough! Stop the arguments and get on with the science of natural killer cell testing
1Ivfaustralia, Westfield Tower 2, 101 Grafton Street, Bondi Junction, Sydney, Australia University of New South Wales, Sydney, Australia St George Hospital and Royal Hospital for Women, Sydney, Australia gsacks@ivf.com.au.
Abstract:
Natural killer cell testing is currently practised widely, and there are studies indicating potential benefit in terms of targeting women with repeated reproductive failure for immune therapy. This may be a better approach than empirical immune therapy without any investigation. More and better studies are needed before such an approach can be fully endorsed. There is still uncertainty over the precise pathophysiological basis for all immune investigation and therapy, but this should not be a barrier for clinical observation and empirical care. On the contrary, clinicians and researchers should work more closely together to provide the best care for our patients.
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