Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Ethics in Research01:56

Ethics in Research

26.3K
Today, scientists agree that good research is ethical in nature and is guided by a basic respect for human dignity and safety. However, this has not always been the case. Modern researchers must demonstrate that the research they perform is ethically sound.
26.3K
Deindividuation00:57

Deindividuation

31.2K
Deindividuation is a form of social influence on an individual’s behavior such that the individual engages in unusual or non-normal behavior while in a group setting. Why? Because in these group settings, the individual no longer sees themselves as an individual anymore, disinhibiting their behavior and personal restraint.
31.2K
Archival Research01:40

Archival Research

17.6K
Some researchers gain access to large amounts of data without interacting with a single research participant. Instead, they use existing records to answer various research questions. This type of research approach is known as archival research. Archival research relies on looking at past records or data sets to look for interesting patterns or relationships. For example, a researcher might access the academic records of all individuals who enrolled in college within the past ten years and...
17.6K
Masking and Demasking Agents01:19

Masking and Demasking Agents

4.0K
EDTA titrations may necessitate masking and demasking agents to temporarily protect a particular metal ion in a mixture from the EDTA reaction. These agents facilitate the sequential analysis of the metal ions by forming stable complexes with some—but not all—metal ions during certain steps.
There are many masking agents, such as cyanide, fluoride, triethanolamine, thiourea, and 2,3-bis(sulfanyl)propan-1-ol (formerly 2,3-dimercapto-1-propanol), with the masking agent chosen based on...
4.0K
Strategies for Assessing and Addressing Confounding01:25

Strategies for Assessing and Addressing Confounding

561
Confounding is a critical issue in epidemiological studies, often leading to misleading conclusions about associations between exposures and outcomes. It occurs when the relationship between the exposure and the outcome is mixed with the effects of other factors that influence the outcome. Given that, addressing confounding is of high importance for drawing accurate inferences in research.
Confounding can be addressed at both the design phase of a study and through analytical methods after data...
561
Blinding01:11

Blinding

4.1K
Blinding is a commonly used method of not telling participants which treatment a subject is receiving. Blinding is a critical part of a randomized control trial or RCT. It reduces the bias that affects the results. In an RCT, blinding is used in the form of a placebo. A placebo effect occurs when untreated subjects falsely believe they have received the treatment and report improved symptoms. A placebo or a dummy treatment is administered to subjects to negate the bias caused by such an effect.
4.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Real-World Outcomes and Prognostic Factors in Patients with Radioiodine-Refractory Differentiated Thyroid Cancer Treated with Sorafenib: A Multicenter Study.

Journal of clinical medicine·2026
Same author

Adjuvant Chemotherapy Regimens in Resected Biliary Tract Cancers: National, Comparative, Observational Study (TOG/GI-SAFRADJU-2501).

International journal of cancer·2026
Same author

Role of liquid biopsy in genitourinary (GU) cancers.

Expert review of molecular diagnostics·2026
Same author

CEA and CA-19-9 Dynamics Associate with Survival in Regorafenib-Treated Metastatic Colorectal Cancer: A Real-World Analysis.

Journal of clinical medicine·2026
Same author

Resectable Stage Early-Onset Biliary Tract Cancer: Survival and Prognostic Scoring (EOB-RS and EOB-OS) in Turkish Patients (TOG/GI-SAFRADJU-2502-EO).

JCO global oncology·2026
Same author

Vaccination in patients with cancer: Gaps in coverage, barriers, and the role of clinician recommendations.

Human vaccines & immunotherapeutics·2026

Related Experiment Video

Updated: Apr 12, 2026

Behavioral Tasks for Examining Identity Recognition In Mice
06:58

Behavioral Tasks for Examining Identity Recognition In Mice

Published on: February 7, 2025

1.3K

The Challenges of Creating a Gold Standard for De-identification Research.

Allen C Browne1, Mehmet Kayaalp1, Zeyno A Dodd1

  • 1Lister Hill National Center for Biomedical Communications, U.S. National Library of Medicine, National Institutes of Health, Bethesda, MD.

AMIA ... Annual Symposium Proceedings. AMIA Symposium
|May 9, 2015
PubMed
Summary

Researchers developed a large dataset of over 20,000 annotated clinical reports. This corpus aids in training and evaluating medical record de-identification software, highlighting the task's complexity.

More Related Videos

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

4.8K
Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

5.9K

Related Experiment Videos

Last Updated: Apr 12, 2026

Behavioral Tasks for Examining Identity Recognition In Mice
06:58

Behavioral Tasks for Examining Identity Recognition In Mice

Published on: February 7, 2025

1.3K
Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting
06:16

Involving Individuals with Developmental Language Disorder and Their Parents/Carers in Research Priority Setting

Published on: June 6, 2020

4.8K
Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community
08:53

Integrating Computerized Linguistic and Social Network Analyses to Capture Addiction Recovery Capital in an Online Community

Published on: May 31, 2019

5.9K

Area of Science:

  • Medical Informatics
  • Natural Language Processing
  • Clinical Data Management

Background:

  • Accurate de-identification of clinical reports is crucial for patient privacy and data utility.
  • Existing datasets may not adequately support the training and evaluation of sophisticated de-identification software.
  • The complexity of narrative clinical text presents challenges for automated processing.

Purpose of the Study:

  • To create a comprehensive Gold Standard corpus for de-identification software development.
  • To provide a robust dataset for training and evaluating the NLM Scrubber system.
  • To document the complexities encountered during the creation of such a corpus.

Main Methods:

  • Compilation of over 20,000 narrative clinical reports.
  • Annotation of reports to establish a Gold Standard for de-identification.
  • Utilizing the corpus for the training and evaluation of the NLM Scrubber software.

Main Results:

  • A Gold Standard corpus exceeding 20,000 annotated clinical records was successfully created.
  • The corpus is suitable for training and evaluating de-identification software like NLM Scrubber.
  • The process revealed significant conceptual challenges inherent in corpus design for this task.

Conclusions:

  • The developed Gold Standard corpus is a valuable resource for advancing medical record de-identification technology.
  • The creation process underscores the need for careful consideration of conceptual complexities in clinical data annotation.
  • This resource facilitates the improvement of privacy-preserving techniques in healthcare informatics.