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Published on: July 12, 2024
Effectiveness of Evidence-Based Congestive Heart Failure (CHF) CPOE Order Sets Measured by Health Outcomes
Jacob Krive1, Joel S Shoolin2, Steven D Zink3
1Advocate Health Care, Oak Brook, IL ; Nova Southeastern University, Fort Lauderdale, FL ; University of Illinois at Chicago, Chicago, IL.
Insights
Evidence-based order sets for congestive heart failure (CHF) reduced patient mortality and length of stay (LOS). However, these order sets did not significantly impact readmission rates.
Area of Science:
- Clinical Medicine
- Health Outcomes Research
- Medical Informatics
Background:
- Evidence-based order sets aim to improve efficiency and consistency in patient care.
- Quantitative data on the effectiveness of order sets, particularly for congestive heart failure (CHF), is limited.
- This study addresses the need for empirical evidence on the impact of CHF order sets.
Purpose of the Study:
- To quantitatively assess the benefits of using evidence-based order sets for congestive heart failure (CHF) treatment.
- To analyze the impact of CHF order sets on key patient outcomes: mortality, readmission rates, and length of stay (LOS).
Main Methods:
- Comparative analysis of adult patients treated with CHF order sets versus free-text orders.
- Logistic regression and chi-squared tests were used to analyze mortality and readmission data.
- ANOVA and Mann-Whitney tests, alongside Charlson Comorbidity Index, were employed to evaluate length of stay (LOS) and comorbidity impact.
Main Results:
- CHF order sets demonstrated a significant reduction in mortality (p=0.034).
- A statistically significant decrease in length of stay (LOS) was observed for patients using order sets (p=0.013).
- No significant difference in readmission rates was found between the order set and free-text groups (p=0.417).
Conclusions:
- Evidence-based order sets for CHF treatment show promise in reducing patient mortality and length of stay (LOS).
- The current evidence suggests that CHF order sets do not significantly affect patient readmission rates.
- Implementing standardized ordering practices for CHF can lead to improved clinical outcomes and resource utilization.
Objective:
Evidence-based order sets for treatment of patients with common conditions promise ordering efficiency and more consistent health outcomes. Despite ongoing utilization of order sets, quantitative evidence of their effectiveness is lacking. This study quantitatively analyzed benefits of CHF order sets as measured by mortality, readmission, and length of stay (LOS) outcomes.
Methods:
Mortality and readmissions were analyzed by comparing "order set" and "free text" groups of adult patients using logistic regression, Pearson chi-squared, and Fisher's exact methods. LOS was calculated by applying One-Way ANOVA and Mann-Whitney tests, supplemented by comorbidity analysis via Charlson Comorbidity Index.
Results:
CHF orders placed via sets were effective in reducing mortality [OR=1.818;95% CF 1.039-3.181;p=0.034] and LOS [F(1,10938)=8.352,p=0.013,4.75 days ("free text" group) vs. 5.46 days ("order set" group)], while readmission outcome was not significant [OR=0.913;95% CF 0.734-1.137;p=0.417].
Conclusion:
Evidence-based medication ordering practices to treat CHF have potential to reduce mortality and LOS, without effect on readmissions.
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Guidelines for Writing Outcome
Patient outcomes reflect the patient's response to the goal rather than what the nurse aims to achieve. Terminology should be observable and measurable to avoid the reader's interpretation. The desired outcome should be realistic and achievable in the designated care timeframe. Expected outcomes should align with adjunctive therapies. The outcome should enhance care...

