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Kodameae ohmeri - An Emerging Yeast: Two Cases and Literature Review

Debadulal Biswal1, Manisa Sahu2, Asmita Mahajan3

  • 1Senior Registrar, Department of Medical Oncology, S L Raheja Hospital , Mahim (W), Mumbai, Maharashtra, India .

Journal of Clinical and Diagnostic Research : JCDR
|May 9, 2015
PubMed

Insights

Kodameae ohmeri is an emerging fungal pathogen causing infections, particularly in immunocompromised individuals and neonates. Early diagnosis and treatment with Amphotericin B were effective in two reported fungemia cases.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Clinical Microbiology

Background:

  • Kodameae ohmeri (K. ohmeri) is an emerging fungal pathogen causing diverse infections.
  • Infections are frequently observed in immunocompromised patients, such as those with cancer.
  • Neonatal infections, especially in premature infants, have been reported with severe outcomes.

Observation:

  • Two cases of fungemia caused by K. ohmeri are presented.
  • The first case involved a patient with hematological malignancy experiencing fever spikes despite antifungal prophylaxis.
  • The second case involved a neonate presenting with respiratory distress and sepsis post-birth.

Findings:

  • Both patients, despite different risk factors, developed K. ohmeri fungemia.
  • Prompt treatment with Amphotericin B led to successful clinical recovery and sterile blood cultures in both cases.
  • K. ohmeri demonstrates increasing prevalence in various infections, affecting both immunocompromised and apparently immunocompetent individuals, including neonates.

Implications:

  • This study highlights K. ohmeri as a significant emerging pathogen requiring clinical vigilance.
  • Effective treatment options, such as Amphotericin B, are crucial for managing K. ohmeri fungemia.
  • Further research is needed to understand the epidemiology and optimal management strategies for K. ohmeri infections.
Keywords:
Amphotericin BFungemiaK. ohmeri

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