Related Experiment Video
Updated: Apr 12, 2026

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
To evaluate the effect of perceived stress on menstrual function
Shahida Nagma1, Garima Kapoor2, Rekha Bharti3
1MBBS Student, Army College of Medical Sciences , Delhi Cantt, New Delhi, India .
High stress levels are linked to menstrual irregularities in women. However, stress does not appear to affect cycle duration, flow amount, or pain, suggesting other causes for these specific menstrual problems.
Area of Science:
- Reproductive Health
- Psychosomatic Medicine
- Women's Health
Background:
- Menstrual irregularities impact 2-5% of women of childbearing age.
- Prevalence of menstrual irregularities is higher in women experiencing chronic stress.
Purpose of the Study:
- To investigate the impact of perceived stress on menstrual cycle length, regularity, and dysmenorrhea.
- To determine the relationship between stress levels and menstrual pattern variations.
Main Methods:
- A cross-sectional study involving 100 female undergraduate medical students.
- Utilized the Perceived Stress Scale (PSS) and Pictorial Blood Assessment Chart (PBAC).
- Statistical analysis included chi-square and Fisher's Exact tests to correlate PSS scores with menstrual patterns.
Main Results:
- 30% of students reported high stress levels (PSS >20).
- A significant association was found between high stress levels and menstrual irregularity.
- No association was observed between high stress levels and hypomenorrhea, menorrhagia, dysmenorrhea, long cycle length, or short cycle length.
Conclusions:
- High perceived stress is associated with menstrual irregularities but not with changes in flow duration, amount, or dysmenorrhea.
- In young women with menstrual problems, other etiological factors should be considered before attributing symptoms solely to stress.
More Related Videos
Related Concept Videos
Psychological Responses to Stress
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
Introduction to Stress and Lifestyle
Physiological Foundation of Stress
Role of the Sympathetic Nervous System
Adrenaline triggers the...
Stress and Mental Health
Individuals with depression often experience challenges in both their personal and professional...
Psychoneuroimmunology: Cardiovascular Disease
A key area of focus in PNI is the relationship between stress and coronary...

