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Updated: Apr 12, 2026

Ultrastructural Localization of Endogenous LC3 by On-Section Correlative Light-Electron Microscopy
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Ultrastructural Localization of Endogenous LC3 by On-Section Correlative Light-Electron Microscopy

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Divergent roles of BECN1 in LC3 lipidation and autophagosomal function

Ruina He1, Jingyu Peng, Pengfei Yuan

  • 1a Biodynamic Optical Imaging Center (BIOPIC); Peking-Tsinghua Center for Life Sciences; State Key Laboratory of Protein and Plant Gene Research; School of Life Sciences; Peking University ; Beijing , China.

Autophagy
|May 9, 2015
PubMed

Keywords:
ATG, autophagy relatedBCL2L1/Bcl-xL, BCL2-like 1BECN1BECN1, Beclin 1, autophagy relatedBECN1P1/BECN2, Beclin 1, autophagy related, pseudogene 1BafA1, bafilomycin A1EM, electron microscopyGAPDH, glyceraldehyde-3-phosphate dehydrogenaseGFP, green fluorescent proteinKO, knockoutLC3MAP1LC3-I/LC3-I, soluble, proteolytically processed microtubule-associated protein 1 light chain 3MAP1LC3-II/LC3-II, proteolytically processed and lipid-modified microtubule-associated protein 1 light chain 3MAP1LC3/LC3, microtubule-associated protein 1 light chain 3MAP1LC3B/LC3B, microtubule-associated protein 1 light chain 3 βPIK3C3/VPS34, phosphatidylinositol 3-kinase, catalytic subunit type 3PIK3R4/VPS15, phosphoinositide-3-kinase, regulatory subunit 4PtdIns3KPtdIns3K, phosphatidylinositol 3-kinaseSQSTM1/p62, sequestosome 1TALEN, transcription activator-like effector nucleaseTUBB, tubulin, β class IUVRAG, UV radiation resistance associatedZFYVE1/DFCP1, zinc finger, FYVE domain containing 1.autophagosomeautophagy

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