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Adipsic hypernatremic myopathy.

Foroogh Sabzghabaei1, Asghar Rastegar

  • 1. fg_sab@yahoo.com.

Iranian Journal of Kidney Diseases
|May 10, 2015
PubMed
Summary

Chronic hypernatremia, a rare condition causing excessive sodium levels due to lack of thirst, can lead to muscle weakness. This case highlights successful treatment through prescribed water intake.

Area of Science:

  • Endocrinology
  • Nephrology
  • Neurology

Background:

  • Chronic hypernatremia is a rare condition characterized by elevated serum sodium levels.
  • It is often associated with a diminished or absent thirst sensation (adipsia).
  • Clinical manifestations can include neurological deficits and muscle abnormalities.

Observation:

  • We present a case of a patient with chronic hypernatremia secondary to adipsia.
  • The patient exhibited significant muscle weakness as a primary symptom.
  • No underlying cause for the adipsia was identified beyond the chronic hypernatremic state.

Findings:

  • The patient's chronic hypernatremia was successfully managed with a regimen of prescribed water intake.
  • Resolution of muscle weakness was observed following normalization of serum sodium levels.

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  • This case underscores the importance of recognizing adipsia as a cause of chronic hypernatremia.

    • Implications:

    • Adipsia-induced chronic hypernatremia, though rare, requires careful diagnosis and management.
    • Prescribed water intake can be an effective therapeutic strategy for this condition.
    • Further research into the mechanisms of adipsia and its neurological consequences is warranted.