Related Experiment Video
Updated: Apr 12, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Isolated congenital maxillomandibular synechiae
Eric W Cerrati1, Omar H Ahmed1, Scott M Rickert1
1Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, NY, USA.
Congenital maxillomandibular syngnathia, a rare jaw fusion, can cause feeding and breathing problems. Simple surgical division of soft tissue bands can effectively treat this condition, improving infant development.
Area of Science:
- Craniofacial Surgery
- Pediatric Surgery
- Developmental Biology
Background:
- Congenital maxillomandibular syngnathia is a rare condition characterized by jaw fusion, leading to feeding, swallowing, and respiratory difficulties.
- This can result in failure to thrive and temporomandibular joint ankylosis, necessitating early intervention for optimal growth.
Purpose of the Study:
- To report a case of isolated soft tissue maxillomandibular syngnathia in a neonate.
- To highlight the effectiveness of simple surgical intervention for this rare condition.
Main Methods:
- A 1-day-old male infant presented with feeding difficulties due to trismus caused by bilateral soft tissue alveolar fibrous bands.
- Surgical division of the fibrous bands was performed under local anesthesia using surgical scissors.
Main Results:
- The infant experienced immediate improvement in mouth opening and resolution of feeding problems post-procedure.
- The patient demonstrated appropriate weight gain and development following the intervention.
Conclusions:
- Isolated maxillomandibular fusion, particularly soft tissue synechiae, is exceptionally rare, with only 11 reported cases.
- Simple surgical division under local anesthesia can be a curative treatment for specific types of maxillomandibular fusion.
More Related Videos
Related Concept Videos
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Structural Joints: Fibrous Joints
Suture
All the bones of the skull, except for the mandible, are joined to each other by a fibrous joint called a suture. The fibrous connective tissue found at a suture strongly unites the adjacent skull bones and thus helps to protect the brain and form the face. In...
Cranial Bones: Superior and Posterior View
The frontal bone is the single bone that forms the forehead. At its anterior midline, between the eyebrows, there is a slight depression called the glabella. The frontal bone also forms the supraorbital margin of the orbit. Near the middle of this margin is the supraorbital foramen, the opening that provides passage for a sensory nerve to the forehead. The frontal bone is thickened just above each supraorbital margin,...
Mitral Stenosis I: Introduction
Cohesins
Cohesin complexes in Meiotic Division
Meiosis involves two distinct rounds of chromosomal segregation and cell divisions— Meiosis I followed by Meiosis II – producing four daughter cells. Meiosis I includes the separation of...

