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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

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Giant cell arteritis: diagnosis and treatment

J M Calvo Romero1

  • 1Servicio de Medicina Interna, Hospital Ciudad de Coria, Coria, Cáceres, España.

Revista Clinica Espanola
|May 11, 2015
PubMed

Insights

Giant cell arteritis, a common vasculitis in older adults, affects large and medium blood vessels. This review covers its diagnosis and treatment strategies for patients over 50.

Area of Science:

  • Rheumatology
  • Internal Medicine
  • Pathology

Background:

  • Giant cell arteritis (GCA) is the most frequent primary systemic vasculitis affecting adults.
  • It is characterized by granulomatous inflammation of large and medium-sized arteries.
  • GCA predominantly impacts individuals aged 50 years and above.

Purpose of the Study:

  • To provide a comprehensive review of the diagnostic approaches for giant cell arteritis.
  • To outline current and emerging treatment strategies for managing GCA.
  • To enhance understanding of this common vasculitic condition in older populations.

Main Methods:

  • Literature review of existing studies on giant cell arteritis.
  • Analysis of diagnostic criteria and imaging techniques.
  • Evaluation of therapeutic options and their efficacy.

Main Results:

  • Early diagnosis is crucial for preventing complications such as vision loss.
  • Corticosteroids remain the cornerstone of treatment, with steroid-sparing agents under investigation.
  • Multidisciplinary approaches improve patient outcomes.

Conclusions:

  • Giant cell arteritis requires prompt recognition and management.
  • Optimal treatment involves balancing efficacy with long-term side effects.
  • Ongoing research aims to refine diagnostic tools and therapeutic regimens.

Keywords:
Arteritis de células gigantesBiopsia de arteria temporalGiant cell arteritisTemporal artery biopsyVasculitis

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