Related Experiment Video For Breast cancer
Updated: Apr 12, 2026
Optimization of Breast Biopsy and Mastectomy Sample Collection Procedures for Biobanking, Personalized Medicine, and Research Applications
Published on: September 2, 2025
Imaging-histological discordance after sonographically guided percutaneous breast core biopsy
Aykut Soyder1, Füsun Taşkin2, Serdar Ozbas3
1Department of General Surgery, Adnan Menderes University Faculty of Medicine, Aydin, Turkey.
Background:
The objectives of this study were to determine the frequency of imaging-histological discordance and to compare the frequency of carcinoma between discordant lesions at ultrasound (US)-guided core needle biopsy.
Materials And Methods:
From November 2009 to June 2012, we performed US-guided 14-gauge core needle biopsies on 989 breast lesions in 961 women. We reviewed 58 (5.8%) cases that had imaging-histological discordance after percutaneous breast biopsy and underwent subsequent excisional biopsy. The clinical, radiological, and histological findings were reviewed for those 58 cases.
Results:
Among the 58 cases, subsequent excisions revealed 16 (27.5%) malignancies, which were categorized as 9 (15.5%) invasive ductal carcinomas, 4 (6.9%) malignant phyllodes tumors, and 3 (5.1%) ductal carcinomas in situ.
Conclusion:
The malignancy rate of 27.5% suggests that surgical excision should be performed in those cases presenting with imaging-histological discordance after US-guided core biopsy. Careful correlation of clinical, radiological, and histological results as well as appropriate follow-up are essential. We have submitted a short version of this work as a poster presentation during the 2012 European Society of Surgery (ESS) Congress in Istanbul/Turkey.
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