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Elastography in pancreatic solid tumours diagnoses.

Przemysław Dyrla1, Jerzy Gil1, Michał Florek1

  • 1Department of Gastroenterology, Military Institute of Medicine, Warsaw, Poland.

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|May 12, 2015
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Summary

Elastography with strain ratio effectively differentiates pancreatic solid tumours. Malignant tumours show higher stiffness than inflammatory or normal tissues, aiding diagnosis.

Keywords:
elasticityelastographyendosonographystrain ratio

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Area of Science:

  • Gastroenterology
  • Medical Imaging
  • Oncology

Background:

  • Diagnosing pancreatic solid tumours is challenging.
  • Endosonography with elastography assesses tissue elasticity for tumour characterization.

Purpose of the Study:

  • Evaluate elastography's utility using the strain ratio method for pancreatic solid tumour evaluation.
  • Quantitatively assess pancreatic solid tumours with elastography.

Main Methods:

  • 54 patients with pancreatic solid tumours underwent endosonography with elastography and fine-needle aspiration.
  • 26 patients with normal pancreas served as controls.
  • Elastography measured elasticity (A) and strain ratio (B/A) in tumours and normal tissue; results compared with histopathology/cytology.

Main Results:

  • Malignant tumours: elasticity (A) 0.025%, strain ratio (B/A) 33.93.
  • Inflammatory tumours: elasticity (A) 0.26%, strain ratio (B/A) 5.35.
  • Normal pancreas: elasticity (A) 0.54%, strain ratio (B/A) 1.79.

Conclusions:

  • Malignant pancreatic tumours exhibit significantly higher stiffness (tightness factor) than inflammatory tumours and normal tissue.
  • Elastography reveals decreasing elasticity from normal to inflammatory to malignant pancreatic tissues.