Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cationic Chain-Growth Polymerization: Mechanism00:57

Cationic Chain-Growth Polymerization: Mechanism

3.1K
The cationic polymerization mechanism consists of three steps: initiation, propagation, and termination. In the initiation step of the polymerization process, the π bond of a monomer gets protonated by the Lewis acid catalyst, which is formed from boron trifluoride and water. The protonation of the π bond generates a carbocation stabilized by the electron‐donating group. In the propagation step, the π bond of the second monomer acts as a nucleophile and attacks the...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward a Comparable Reactivity Framework for Type I Photoinitiators in Photocleavage, Photopolymerization and Light-Driven Additive Manufacturing.

Journal of the American Chemical Society·2026
Same author

Macromolecules with Tunable Fluorescence via Photochemical Step-Growth Polymerization.

ACS macro letters·2026
Same author

Understanding Wavelength-Dependent Photopolymerizations via Nano-Second Resolved Transient Spectroscopy.

Journal of the American Chemical Society·2026
Same author

Following the formation of single-chain nanoparticles generated by interblock crosslinking within diblock copolymers: a Monte Carlo simulation study with adjustable interaction strength between the blocks.

Soft matter·2026
Same author

Wavelength-Dependent 3D Printing: Introducing 3D Printed Action Plots.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Wavelength-resolved heterodimer [2 + 2] photocycloadditions for reversible surface grafting.

Chemical science·2026

Related Experiment Video

Updated: Apr 12, 2026

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

4.3K

Phototriggered functionalization of hierarchically structured polymer brushes.

Andres de los Santos Pereira1, Nina Yu Kostina1, Michael Bruns2

  • 1†Institute of Macromolecular Chemistry, Academy of Sciences of the Czech Republic, v.v.i., Heyrovsky sq. 2, 162 06 Prague, Czech Republic.

Langmuir : the ACS Journal of Surfaces and Colloids
|May 12, 2015
PubMed
Summary

We developed novel antifouling polymer brushes with hierarchical structures using surface-initiated atom transfer radical polymerization (SI-ATRP). These brushes enable precise biofunctionalization for advanced biomedical applications and biosensing.

More Related Videos

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.8K
Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

14.4K

Related Experiment Videos

Last Updated: Apr 12, 2026

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization
07:28

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

4.3K
Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers
10:09

Fabricating Reactive Surfaces with Brush-like and Crosslinked Films of Azlactone-Functionalized Block Co-Polymers

Published on: June 30, 2018

8.8K
Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes
13:57

Preparation and Friction Force Microscopy Measurements of Immiscible, Opposing Polymer Brushes

Published on: December 24, 2014

14.4K

Area of Science:

  • Materials Science
  • Polymer Chemistry
  • Surface Science

Background:

  • Precise design of bioactive surfaces is crucial for biomedical applications.
  • Controlling surface architecture and attaching bioreceptors to antifouling surfaces are key challenges.

Purpose of the Study:

  • To develop a facile method for creating hierarchically structured antifouling polymer brushes.
  • To enable precise spatial control over surface biofunctionalization.
  • To demonstrate the utility of these surfaces in biosensing applications.

Main Methods:

  • Surface-initiated atom transfer radical polymerization (SI-ATRP) of oligo(ethylene glycol) methacrylates.
  • Photoclick chemistry utilizing tetrazole moieties for functionalization via nitrile imine-mediated tetrazole-ene cyclocloaddition (NITEC).
  • Graft-on-graft polymer architecture generation and characterization using X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS).

Main Results:

  • Hierarchically structured, antifouling polymer brushes with photoactive tetrazole groups were successfully synthesized.
  • Spatially resolved biofunctionalization was achieved through photoligation of biotin-maleimide and streptavidin binding.
  • Functionalized brushes demonstrated significant resistance to blood plasma fouling (90% reduction).
  • A model biosensor was developed by immobilizing antibodies for antigen capture, monitored by surface plasmon resonance.

Conclusions:

  • The developed method provides a versatile platform for creating advanced bioactive surfaces.
  • The hierarchically structured antifouling brushes offer excellent resistance to biofouling.
  • The spatially controlled biofunctionalization enables sensitive biosensing applications.